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| Coelho,A.M.M.; Machado,M.C.C.; Sampietre,S.N.; Leite,K.R.M.; Oliveira,V.L.L.; Pinotti,H.W.. |
| We studied the alterations in the metabolism of liver mitochondria in rats with acute pancreatitis. Male Wistar rats were allocated to a control group (group I) and to five other groups corresponding to 2, 4, 12, 24 and 48 h after the induction of acute pancreatitis by the injection of 5% sodium taurocholate into the pancreatic duct. Sham-operated animals were submitted to the same surgical steps except for the induction of acute pancreatitis. Mitochondrial oxidation and phosphorylation were measured polarographically by determining oxygen consumption without ADP (basal respiration, state 4) and in the presence of ADP (activated respiration, state 3). Serum amylase, transaminases (ALT and AST) and protein were also determined. Ascitic fluid, contents of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Acute pancreatitis; Hepatic lesion; Mitochondria. |
| Ano: 1997 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000800006 |
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