Home Itens selecionados Provedores de dados OAI Créditos Sobre Ajuda

			Busca avançada
	Provedor de dados Anais da ABC (AABC) (1) Biol. Res. (1) Autor CECCONELLO,DAIANE K. (1) ESPARZA,ANDRÉS L (1) FALCETTA,FREDERICO S. (1) FAULHABER,GUSTAVO A.M. (1) MARCONDES,NATÁLIA A. (1) MENA,NATALIA P (1) NÚÑEZ,MARCO T (1) PILGER,DIOGO A. (1) RAUBER,MARIANA R. (1) Mais... Palavra-chave Hepcidin (2) Caco-2 cells (1) DMT1 (1) Diagnostic screening (1) Ferritin (1) Iron (1) Iron absorption (1) Metabolic syndrome (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Journal article (1) Ano 2019 (1) 2006 (1) País Brazil (1) Chile (1) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Hepcidin is a useful biomarker to evaluate hyperferritinemia associated with metabolic syndrome Anais da ABC (AABC) RAUBER,MARIANA R.; PILGER,DIOGO A.; CECCONELLO,DAIANE K.; FALCETTA,FREDERICO S.; MARCONDES,NATÁLIA A.; FAULHABER,GUSTAVO A.M.. Abstract: Investigation of hyperferritinemia in metabolic syndrome patients represents a diagnostic challenge, but it is essential for the identification of individuals with iron overload. Hepcidin negatively regulates iron absorption and release. An increase in hepcidin occurs when iron levels are sufficient or in inflammatory states, conditions often associated with hyperferritinemia. Hemochromatosis causes hyperferritinemia due to iron overload, but frequently has low hepcidin levels. Our aim was to evaluate biochemical and molecular parameters related to iron metabolism in patients with metabolic syndrome. We evaluated 94 patients with metabolic syndrome according to the International Diabetes Federation criteria in a cross-sectional study.... Tipo: Info:eu-repo/semantics/article Palavras-chave: Diagnostic screening; Ferritin; Hepcidin; Iron; Metabolic syndrome. Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000300803 Regulation of transepithelial transport of iron by hepcidin Biol. Res. MENA,NATALIA P; ESPARZA,ANDRÉS L; NÚÑEZ,MARCO T. Hepcidin (Hepc) is a 25 amino acid cationic peptide with broad antibacterial and antifungal actions. A likely role for Hepc in iron metabolism was suggested by the observation that mice having disruption of the gene encoding the transcription factor USF2 failed to produce Hepc mRNA and developed spontaneous visceral iron overload. Lately, Hepc has been considered the "stores regulator," a putative factor that signals the iron content of the body to intestinal cells. In this work, we characterized the effect of Hepc produced by hepatoma cells on iron absorption by intestinal cells. To that end, human Hepc cDNA was cloned and overexpressed in HepG2 cells and conditioned media from Hepc-overexpressing cells was used to study the effects of Hepc on intestinal... Tipo: Journal article Palavras-chave: Hepcidin; Iron absorption; DMT1; Caco-2 cells. Ano: 2006 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602006000100022 Registros recuperados: 2 Primeira ... 1 ... Última

Empresa Brasileira de Pesquisa Agropecuária - Embrapa Todos os direitos reservados, conforme Lei n° 9.610 Política de Privacidade Área restrita		Embrapa Parque Estação Biológica - PqEB s/n° Brasília, DF - Brasil - CEP 70770-901 Fone: (61) 3448-4433 - Fax: (61) 3448-4890 / 3448-4891 SAC: https://www.embrapa.br/fale-conosco