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| Laval,Cristina Aparecida Borges; Pimenta,Fabiana Cristina; Andrade,João Guimarães de; Andrade,Soraya S.; Andrade,Ana Lucia S. S. de. |
| Acute bacterial meningitis is an important cause of morbidity and mortality among children less than five years old. Haemophilus influenzae, Streptococcus pneumoniae and Neisseria meningitidis are the most important agents of bacterial meningitis in developing countries. The development of the conjugate vaccines in the beginning of the 90's, especially type b H. influenzae (Hib), and more recently the heptavalent pneumococcal and the serogroup C meningococcal vaccines, have contributed directly to changes in the epidemiological profile of these invasive diseases (direct effect) and of their carriage status (indirect effect). We review the impact of the Hib conjugate vaccine in Latin American countries, where this vaccine has been implemented, and the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Conjugate vaccines; Hib conjugate vaccine; Pneumococcal conjugate vaccine; Meningococcal conjugate vaccine; Impact of Hib conjugate vaccine. |
| Ano: 2003 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000500006 |
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| de Almeida,A.E.C.C.; de Filippis,I.; Abreu,A.O. de; Ferreira,D.G.; Gemal,A.L.; Marzochi,K.B.F.. |
| Few vaccines in history have induced such a dramatic decline in incidence over such a short period of time as the Haemophilus influenzae type b (Hib) conjugate. This vaccine was introduced in 1988 in the United States, but only in 1999 was Hib immunization introduced by the Brazilian Ministry of Health as part of the routine infant National Immunization Program. The authors analyzed 229 H. influenzae (Hi) isolates from Public Health Laboratories in three Brazilian states: Pernambuco (Northeast, N = 54), Santa Catarina (South, N = 19), and Rio de Janeiro (Southeast, N = 156). The isolates were collected from Brazilian children 0-10 years of age with meningitis and other infections from 1990 to 2003 and were part of the research collection of the National... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Haemophilus influenzae; Haemophilus influenzae non-b; Hib conjugate vaccine; Immunization; Hib meningitis. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000500016 |
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