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	Provedor de dados BJPS (2) Autor Chassot,Janaíne Micheli (1) Cruz,Letícia (1) Ferreira,Luana Mota (1) Gomes,Felipe Pereira (1) Khalil,Najeh Maissar (1) Mainardes,Rubiana Mara (1) Rodrigues,Caroline Danziato (1) Tasso,Leandro (1) Mais... Palavra-chave High performance liquid chromatography/reverse phase/quantitative analysis (2) Amphotericin B/determination (1) Amphotericin B/encapsulation (1) Beclomethasone dipropionate/determination (1) Nanocapsule/suspensions (1) Nanoparticles (1) Nanoparticles. (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2015 (1) 2014 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Stability-indicating RP-HPLC method for determination of beclomethasone dipropionate in nanocapsule suspensions BJPS Chassot,Janaíne Micheli; Ferreira,Luana Mota; Gomes,Felipe Pereira; Cruz,Letícia; Tasso,Leandro. abstract A simple stability-indicating RP-HPLC/UV method was validated for determination of beclomethasone dipropionate (BD) in nanocapsule suspensions. Chromatographic conditions consisted of a RP C18column (250 mm x 4.60 mm, 5 µm, 110 Å), using methanol and water (85:15 v/v) as mobile phase at 1.0 mL/min with UV detection at 254 nm. The calibration curve was found to be linear in the concentration range of 5.0-25.0 µg/mL with a correlation coefficient > 0.999. Precision was demonstrated by a relative standard deviation lower than 2.0%. Accuracy was assessed by the recovery test of BD from nanocapsules (98.03% to 100.35%). Specificity showed no interference from the components of nanocapsules or from the degradation products derived from acid, basic... Tipo: Info:eu-repo/semantics/article Palavras-chave: High performance liquid chromatography/reverse phase/quantitative analysis; Beclomethasone dipropionate/determination; Nanocapsule/suspensions; Nanoparticles.. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000400803 Determination of amphotericin B in PLA-PEG blend nanoparticles by HPLC-PDA BJPS Rodrigues,Caroline Danziato; Khalil,Najeh Maissar; Mainardes,Rubiana Mara. In this work, we developed and validated an effective reversed-phase HPLC method with photodiode array (PDA) detection for the quantitative analysis of amphotericin B (AmB) in poly(lactide)-poly(ethylene glycol) (PLA-PEG) blend nanoparticles. Chromatographic runs were performed on a reverse phase C18 column using a mobile phase comprising a 9% acetic acid and acetonitrile mixture (40:60, v/v) under isocratic elution with a flow rate of 1 mL/min. AmB was detected at a wavelength of 408 nm. The validation process was performed considering the selectivity, linearity, precision, accuracy, robustness, limit of detection (LOD) and limit of quantitation (LOQ) of the method. A concentration range of 1-20 µg/mL was used to construct a linear calibration curve. The... Tipo: Info:eu-repo/semantics/article Palavras-chave: Amphotericin B/determination; Amphotericin B/encapsulation; High performance liquid chromatography/reverse phase/quantitative analysis; Nanoparticles. Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502014000400859 Registros recuperados: 2 Primeira ... 1 ... Última

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