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Sesame radiatum Phytoestrogens Stimulate Spermatogenic Activity and Improve Sperm Quality in Adult Male Sprague Dawley Rat Testis International Journal of Morphology
Shittu,Lukeman, A. J.; Shittu,Remilekun, K.; Adesite,Samson, O.; Ajala,M. Oluwole; Bankole,Munir, A.; Benebo,A. S.; Tayo,A. O.; Ogundipe,Olufemi, A.; Ashiru,Oladapo, A..
Increasing concern has been expressed about the declining sperm count of humans and the potential environmental effects of both synthetic and natural estrogenic endocrine disruptors (EEDs) on human reproductive health in the last few decades. However, due to paucity of knowledge, we evaluate the chronic reproductive toxicity of sesame phytoestrogenic lignans on the male Sprague Dawley (SD) rats' testis. Thirty adult male SD rats weighing 150-200g were divided into three groups. Two treated groups received a daily dose of aqueous leaves extract of Sesamum radiatum at 14.0 mg/kg bw and 28.0mg /kg bw respectively via gastric gavage, while equal volume of normal saline was administered to the control group for six weeks. Seminal analysis and hormonal assay...
Tipo: Journal article Palavras-chave: Testis; Sesame leaves; Histopathology; Hormonal assay; Seminal analysis; SD Rats.
Ano: 2008 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022008000300022
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