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Ohe,M.N.; Santos,R.O.; Barros,E.R.; Lage,A.; Kunii,I.S.; Abrahão,M.; Cervantes,O.; Hauache,O.M.; Lazaretti-Castro,M.; Vieira,J.G.H.. |
In contrast to most developed countries, most patients with primary hyperparathyroidism in Brazil are still symptomatic at diagnosis. However, we have been observing a change in this pattern, especially in the last few years. We evaluated 104 patients, 77 females and 27 males aged 11-79 years (mean: 54.4 years), diagnosed between 1985 and 2002 at a University Hospital. Diagnosis was made on the basis of clinical findings and of high total and/or ionized calcium levels, high or inappropriate levels of intact parathyroid hormone and of surgical findings in 80 patients. Patients were divided into three groups, i.e., patients diagnosed from 1985 to 1989, patients diagnosed from 1990 to 1994, and patients diagnosed from 1995 to 2002. The number of new cases... |
Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Primary hyperparathyroidism; Hypercalcemia; Clinical presentation; Asymptomatic primary hyperparathyroidism; Parathyroid hormone; Hyperparathyroidism. |
Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000900013 |
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Oliveira,U.E.M.; Ohe,M.N.; Santos,R.O.; Cervantes,O.; Abrahão,M.; Lazaretti-Castro,M.; Vieira,J.G.H.; Hauache,O.M.. |
Primary hyperparathyroidism is an endocrine disorder with variable clinical expression, frequently presenting as asymptomatic hypercalcemia in Western countries but still predominantly as a symptomatic disease in developing countries. The objective of this retrospective study was to describe the diagnostic presentation profile, parathyroidectomy indication and post-surgical bone mineral density follow-up of patients with primary hyperparathyroidism seen at a university hospital. We found 115 patients (92 women, median age 56 years) with primary hyperparathyroidism diagnosed during the last 20 years. We defined symptomatic patients based on the presence of any classical symptom affecting bone, kidney or the neuromuscular system. Surgical criteria followed... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Primary hyperparathyroidism; Hypercalcemia; Clinical presentation; Parathyroidectomy; Bone mineral density. |
Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000400010 |
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