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	Provedor de dados BJMBR (2) Autor Azevedo,L.C.P. (1) Batista,A. (1) Biagini,S. (1) Carvalho,C.R.R. (1) Castro,L. (1) Dale,C.S. (1) De Castro-e-Silva,E. (1) Duque,B. (1) Fregoneze,J.B. (1) Luz,P. (1) Moreira,E.S. (1) Real,J.M. (1) Rocha Junior,M.A. (1) Santana,R. (1) Schettino,G.P.P. (1) Silva,I. (1) Varjão,B. (1) Wendel,S. (1) Mais... Palavra-chave Hypovolemia (2) 5-HT4 receptors (1) Hemorrhage (1) Hyperosmolarity (1) Inflammation (1) Red blood cells (1) Swine (1) Transfusion (1) Water intake (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Info:eu-repo/semantics/other (1) Ano 2018 (1) 2001 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Short-term effects of stored homologous red blood cell transfusion on cardiorespiratory function and inflammation: an experimental study in a hypovolemia model BJMBR Biagini,S.; Dale,C.S.; Real,J.M.; Moreira,E.S.; Carvalho,C.R.R.; Schettino,G.P.P.; Wendel,S.; Azevedo,L.C.P.. The pathophysiological mechanisms associated with the effects of red blood cell (RBC) transfusion on cardiopulmonary function and inflammation are unclear. We developed an experimental model of homologous 14-days stored RBC transfusion in hypovolemic swine to evaluate the short-term effects of transfusion on cardiopulmonary system and inflammation. Sixteen healthy male anesthetized swine (68±3.3 kg) were submitted to controlled hemorrhage (25% of blood volume). Two units of non-filtered RBC from each animal were stored under blood bank conditions for 14 days. After 30 min of hypovolemia, the control group (n=8) received an infusion of lactated Ringer's solution (three times the removed volume). The transfusion group (n=8) received two units of homologous... Tipo: Info:eu-repo/semantics/article Palavras-chave: Swine; Transfusion; Inflammation; Red blood cells; Hypovolemia; Hemorrhage. Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000100604 Effect of the intracerebroventricular administration of GR 113808, a selective 5-HT4 antagonist, on water intake during hyperosmolarity and hypovolemia BJMBR Castro,L.; Varjão,B.; Silva,I.; Duque,B.; Batista,A.; Santana,R.; Luz,P.; Rocha Junior,M.A.; Fregoneze,J.B.; De Castro-e-Silva,E.. We demonstrate here that acute third ventricle injections of GR 113808, a highly selective 5-HT4 antagonist, decrease water intake induced by a previous salt load while potentiating drinking elicited by hypovolemia induced by previous subcutaneous administration of polyethylene glycol in male Wistar rats (200 ± 20 g). At the dose of 160 nmol/rat, third ventricle injections of GR 113808 induced a significant reduction of water intake in salt-loaded animals after 120 min as compared to salt-loaded animals receiving third ventricle injections of saline (salt load + GR = 3.44 ± 0.41 ml, N = 12; salt load + saline = 5.74 ± 0.40 ml, N = 9). At the dose of 80 nmol/rat, GR 113808 significantly enhanced water intake in hypovolemic animals after 120 min as compared... Tipo: Info:eu-repo/semantics/other Palavras-chave: 5-HT4 receptors; Water intake; Hyperosmolarity; Hypovolemia. Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000600015 Registros recuperados: 2 Primeira ... 1 ... Última

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