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| Oliveira Jr.,E.B.; Ferraz,M.L.G.; Perez,R.M.; Silva,A.E.B.; Lanzoni,V.P.; Granato,C.F.. |
| The objectives of the present study were to assess the in vitro-induced anti-hepatitis C virus (HCV) antibody production (IVIAP) in relation to the clinical, biochemical, virologic and histologic variables of patients with HCV infection. The study included 57 patients (60% males) with HCV infection (anti-HCV and HCV-RNA positive). Alanine aminotransferase (ALT) was elevated in 89% of the patients. Mean viral load was 542,241 copies/ml and histology of the liver showed chronic hepatitis in 27/52 (52%) and cirrhosis in 11/52 (21%) patients. IVIAP levels were determined by immunoenzymatic assay at median absorbance of 0.781 at 450 nm. IVIAP was negative in 14% of the patients. When groups with IVIAP levels above and below the median were compared, high IVIAP... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hepatitis C; In vitro-induced antibody production; IVIAP; Hepatitis C virus-RNA; Liver biopsy; Anti-HCV antibodies. |
| Ano: 2003 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000300011 |
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