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| ABREU,DILAYLA K. DE; MONTEIRO,JANAINA M.; SOUZA,CAROLINA C.; KARAM,RAFAEL G.; FERNANDES,RENATA A.; LESSA,THAIS B.; FAGLIARI,JOSÉ J.; MIGLINO,MARIA ANGELICA; AMBROSIO,CARLOS EDUARDO. |
| Abstract Duchenne Muscular Dystrophy (DMD) is the most common X-linked muscular disease affecting humans. The Golden Retriever Muscular Dystrophy model (GRMD) is considerthe most suitable for several studies. This assay aims to quantify lymphocyte subpopulations CD4, CD5, and CD8, and standardize, the serum electrophoretic profile, to understand their contribution to the pathologic process in normal Golden Retriever dogs (GR group) and dystrophic´s (GRMD group), through the umbilical cord blood, in dogs aged from 2 to 3 months (GR II and GRMD II), and in dogs over 1 year of age (GR III and GRMD III). No significant differences were observed between the CD8+ lymphocyte subpopulations of the groups studied. The CD4+ and CD5+ lymphocyte subpopulations were... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Acute phase protein; Dystrophic model; Immune behavior; Inflammatory response; Muscular dystrophy; Serum protein. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000602977 |
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