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	Provedor de dados BJMBR (1) BJM (1) Autor Corbett,C.E.P. (1) Costa,J.M.L. (1) Gama,M.E.A. (1) Gomes,C.M.C. (1) Haanwinckel,Maria Cristina Santos (1) Oliveira,Silvio Luis de (1) Pereira,J.C.R. (1) Mais... Palavra-chave Immunological aspects (2) Biozzi mice (1) Cytokine levels (1) Cytokines (1) Leptospira (1) Macrophages (1) Oligosymptomatic form (1) Subclinical form (1) Visceral leishmaniasis (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2011 (1) 2004 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Serum cytokine profile in the subclinical form of visceral leishmaniasis BJMBR Gama,M.E.A.; Costa,J.M.L.; Pereira,J.C.R.; Gomes,C.M.C.; Corbett,C.E.P.. The factors determining the development or not of visceral leishmaniasis (VL) have not been completely identified, but a Leishmania-specific cellular immune response seems to play a fundamental role in the final control of infection. Few studies are available regarding the production of cytokines in the subclinical form of VL, with only the production of IFN-g and TNF-a known. The aim of the present study was to identify immunological markers for the oligosymptomatic or subclinical form of VL. A prospective cohort study was conducted on 784 children aged 0 to 5 years from an endemic area in the State of Maranhão, Brazil, between January 1998 and December 2001. During 30 consecutive months of follow-up, 33 children developed the oligosymptomatic form of the... Tipo: Info:eu-repo/semantics/article Palavras-chave: Visceral leishmaniasis; Cytokine levels; Immunological aspects; Subclinical form; Oligosymptomatic form. Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000100018 Production of reactive oxygen (H2O2) and nitrogen (NO) intermediates and TNF-α in mice genetically selected for high (H) and low (L) antibody response and experimentally infected with Leptospira serovar pomona BJM Haanwinckel,Maria Cristina Santos; Oliveira,Silvio Luis de. The aim of the present study was to evaluate the activity of macrophages, and the production of TNF-α and antibodies against experimental infection by Leptospira serovar Pomona in mice genetically selected for High (H) or Low (L) humoral immune response. To evaluate macrophagic activity, peritoneal and splenic lavages were performed for determination of oxygen (H2O2) and nitrogen (NO) intermediates. The production of the tumor necrosis factor (TNF-α) was investigated through bioassays in serum and homogenates of splenic and hepatic cells of control and infected animals, as was as specific antibodies production. The immune response against serovar Pomona in those lines, was characterized by high antibody production, especially in later periods of the... Tipo: Info:eu-repo/semantics/article Palavras-chave: Immunological aspects; Biozzi mice; Leptospira; Macrophages; Cytokines. Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822011000200041 Registros recuperados: 2 Primeira ... 1 ... Última

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