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| Tsuboy,Marcela Stefanini; Marcarini,Juliana Cristina; Ferreira,Dalva Trevisan; Ferraz,Elisa Raquel Anastácio; Chequer,Farah Maria Drumond; Oliveira,Danielle Palma de; Ribeiro,Lúcia Regina; Mantovani,Mário Sérgio. |
| The common everyday use of medicinal plants is an ancient, and still very widespread practice, whereby the need for studies on their possible toxicity and mutagenic properties. The species Coccoloba mollis has been much used in phytotherapy, mainly in cases involving loss of memory and stress. In order to investigate its genotoxic and mutagenic potential, ethanolic extracts from the leaves and roots underwent Salmonella/microsome assaying (TA98 and TA100 strains, with and without exogenous metabolism - S9), besides comet and micronucleus tests in vivo.There was no significant increase in the number of revertants/plate of Salmonella strains in any of the analyzed root-extract concentrations, although the extract itself was extremely toxic to the Salmonella... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Medicinal plants; Coccoloba mollis; Ames test; In vivo comet assay; In vivo micronucleus assay; Polygonaceae. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572010000300027 |
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