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Effects of natural aging and gender on pro-inflammatory markers BJMBR
Milan-Mattos,J.C.; Anibal,F.F.; Perseguini,N.M.; Minatel,V.; Rehder-Santos,P.; Castro,C.A.; Vasilceac,F.A.; Mattiello,S.M.; Faccioli,L.H.; Catai,A.M..
The term inflammaging is now widely used to designate the inflammatory process of natural aging. During this process, cytokine balance is altered, presumably due to the loss of homeostasis, thus contributing to a greater predisposition to disease and exacerbation of chronic diseases. The aim of the study was to analyze the relationship between pro-inflammatory markers and age in the natural aging process of healthy individuals. One hundred and ten subjects were divided into 5 groups according to age (22 subjects/group). Interleukin-6 (IL-6) and tumor necrosis factor α (TNF-α) were quantified using the ELISA method. High-sensitivity C-reactive protein (hsCRP) was analyzed by turbidimetry according to laboratory procedures. The main findings of this study...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Natural aging; Inflammaging; Immune system; HsCRP; IL-6.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019000900601
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