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	Provedor de dados ArchiMer (1) Autor Green, Timothy (1) Montagnani, Caroline (1) Palavra-chave Crassostrea gigas (1) Interferon-like response (1) OsHV-1 (1) Poly I:C (1) Vibrio splendidus (1) Tipo do documento Text (1) Ano 2013 (1) País France (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Poly I:C induces a protective antiviral immune response in the Pacific oyster (Crassostrea gigas) against subsequent challenge with Ostreid herpesvirus (OsHV-1 mu var) ArchiMer Green, Timothy; Montagnani, Caroline. In-vivo studies were carried out to investigate the protective effect of a synthetic viral analogue (poly I:C) against Ostreid herpes virus (OsHV-1 mu var). Pacific oysters (Crassostrea gigas) were immune-primed by intramuscular injection of 240 mu g of poly I:C or sterile seawater at 1 day prior to infection with OsHV-1 mu var. Poly I:C injection induced an antiviral state in C gigas as the percentage of viral-infected oysters at 48 h post infection was significantly lower in the poly I:C treatment (11%) compared to seawater controls (100%). In an additional experiment, we demonstrated that the protective role of poly I:C is reproducible and elicits a specific antiviral response as immune-priming with heat-killed Vibrio splendidus provided no protection... Tipo: Text Palavras-chave: Crassostrea gigas; OsHV-1; Poly I:C; Vibrio splendidus; Interferon-like response. Ano: 2013 URL: http://archimer.ifremer.fr/doc/00152/26293/24739.pdf Registros recuperados: 1 Primeira ... 1 ... Última

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