|
|
|
|
|
| Dettino,A.L.A.; Duarte,A.J.S.; Sato,M.N.. |
| We studied the effect of oral and portal vein administration of alloantigens on mouse skin allograft survival. Graft receptor BALB/c mice received spleen cells (30, 90, 150 or 375 x 10(6)) from donor C57BL/6 mice intragastrically on three successive days, starting seven days before the skin graft. Allograft survival was significantly increased with the feeding of 150 x 10(6) allogeneic spleen cells by one gavage (median survival of 12 vs 14 days, P <= 0.005) or when 300 x 10(6) cells were given in six gavage (12 vs 14 days, P < 0.04). A similar effect was observed when 150 x 10(6) spleen cells were injected into the portal vein (12 vs 14 days, P <= 0.03). Furthermore, prolonged allograft survival was observed with subcutaneous (12 vs 16 days, P... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Mouse oral tolerance; Intraportal route; Skin transplantation; Interleukin-4; Alloantigen. |
| Ano: 2004 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000300022 |
| |
|
|
| Pitrez,P.M.C.; Machado,D.C.; Jones,M.H.; Andrade,F.; Camozzato,C.; Stein,R.T.. |
| Wheezing associated with respiratory viral infections in infancy is very common and results in high morbidity worldwide. The Th1/Th2 pattern of immune response in these patients remains unclear and previous studies have shown controversial results. The aim of the present study was to compare the type of Th1/Th2 cytokine response between infants with acute bronchiolitis, recurrent wheezing and upper respiratory infections from a developing country. Infants younger than 2 years of age admitted to Hospital São Lucas, Porto Alegre, RS, Brazil, between May and November 2001, with an acute episode of wheezing associated with viral respiratory infection were selected. Subjects with upper respiratory infections from the emergency department were selected for the... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Acute bronchiolitis; Inflammation; Interferon-gamma; Interleukin-4; Cytokines. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000100008 |
| |
|
|
|
