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Treatment of cytomegalovirus retinitis with an intraocular sustained-release ganciclovir implant BJMBR
Muccioli,C.; Belfort Jr.,R..
The objective of this prospective study was to evaluate the efficacy and complications of the use of an intraocular sustained-release ganciclovir implant for the treatment of active cytomegalovirus (CMV) retinitis in AIDS patients. Thirty-nine eyes of 26 patients were submitted to ocular surgery. All patients underwent complete ocular examination before and after surgery. The surgical procedure was always done under local anesthesia using the same technique. The mean time for the surgical procedure was 20 min (range, 15 to 30 min). The average follow-up period was 3.7 months. Of all patient, only 4 presented recurrence of retinitis after 8, 8, 9 and 2 months, respectively. Three of them received a successful second implant. All 39 eyes of the 26 patients...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cytomegalovirus; Retinitis; Intraocular inflammation; AIDS; Uveitis.
Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000700008
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Firocoxib on aqueous humor prostaglandin E 2 levels for controlling experimentally-induced breakdown of blood-aqueous barrier in healthy and Toxoplasma gondii -seropositive cats Ciência Rural
Schroder,Deise Cristine; Stocco,Matias Bassinello; Isoton,Deborah de Arruda; Silva,Carla Patricia Amarante e; Braga,Ísis Assis; Silva,Érica Pereira da; Maciel,Camila do Espírito Santo; Maruyama,Fernanda Harumi; Nakazato,Luciano; Aguiar,Daniel Moura de; Mendonça,Adriane Jorge; Ribeiro,Alexandre Pinto.
ABSTRACT: This study aimed to evaluate the effects of firocoxib for controlling experimentally-induced breakdown of the blood-aqueous barrier in healthy and Toxoplasma gondii -seropositive cats. Thirty two cats with no ocular abnormalities were used. Groups (n=8/each) were formed with healthy cats that received 5mg g-1 of oral firocoxib (FH) or no treatment (CH) on day 0; seropositive cats for anti -T. gondii specific immunoglobulin G (IgG) were grouped (n=8/each) and treated in a similar fashion (FT and CT). On day 1, cats of all groups received the same treatment protocol, and 1h later, aqueocentesis was performed under general anesthesia (M0). Following 1h, the same procedure was repeated (M1). Quantitation of aqueous humor total protein and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Aqueous humor; Intraocular inflammation; NSADs; Toxoplasmosis.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782016000601053
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