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| Hubka, V.; Barrs, V.; Dudová, Z.; Sklenář, F.; Kubátová, A.; Matsuzawa, T.; Yaguchi, T.; Horie, Y.; Nováková, A.; Frisvad, J.C.; Talbot, J.J.; Kolařík, M.. |
| Although Aspergillus fumigatus is the major agent of invasive aspergillosis, an increasing number of infections are caused by its cryptic species, especially A. lentulus and the A. viridinutans species complex (AVSC). Their identification is clinically relevant because of antifungal drug resistance and refractory infections. Species boundaries in the AVSC are unresolved since most species have uniform morphology and produce interspecific hybrids in vitro. Clinical and environmental strains from six continents (n = 110) were characterized by DNA sequencing of four to six loci. Biological compatibilities were tested within and between major phylogenetic clades, and ascospore morphology was characterised. Species delimitation methods based on the multispecies... |
| Tipo: Article / Letter to the editor |
Palavras-chave: Aspergillus felis; Aspergillus fumigatus; Invasive aspergillosis; Mating-type genes; Multispecies coalescence model; Neosartorya udagawae; Scanning electron microscopy; Soil fungi. |
| Ano: 2018 |
URL: http://www.repository.naturalis.nl/record/652411 |
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