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Effect of Visfatin on the Structure and Immune Levels in the Small Intestine of LPS-Induced Rats International Journal of Morphology
Zhou,Ying; Cui,Lu; Yuan,Huairui; Xiao,Ke; Khan,Faheem Ahmed; Guo,Liang; Yang,Zhi; Song,Hui.
This study investigated the effects of visfatin on the structure and the immunity levels in the small intestine of LPS-induced rats. Forty Wistar male and female SPF rats were randomly and equally divided into four groups: the saline (control), vistfatin, lipopolysaccharide (LPS), and visfatin+LPS co-stimulated. The functions of visfatin in the intestinal mucosal immunity were investigated by examining the variation of tissue structure, inflammation and immunity-related proteins in the intestine of immunologically stressed rats using HE staining, ELISA, immunohistochemistry and Western Blot. The results showed that, when compared with the control group, the visfatin-treated group showed a decrease in the intestinal villus height and width, and a...
Tipo: Journal article Palavras-chave: Visfatin; Intestinal mucosa; LPS­induced rats; IgA; Inflammatory factor.
Ano: 2015 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022015000400051
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