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| Campebell,R.C.; Peiró,J.R.; Valadão,C.A.A.; Santana,A.E.; Cunha,F.Q.. |
| Lidocaine (100mg 2%) injected into the carpal joint was used to evaluate the inflammatory response induced by injection (1.5ng) of intra-articular E. coli lipopolysaccharide (LPS) endotoxin. Seventeen male Mangalarga horses aged two to three years were divided into three groups and in all animals was injected 0.9% saline (SAL) in the left carpus (LC), and in the right carpus (RC) one of the following combinations were injected: group A (n=6) LPS plus SAL; group B (n=6) LPS plus lidocaine; group C (n=5) lidocaine plus SAL. Synovial fluid and blood samples were collected immediately before the injection of LPS (T0), and at 1.5 (T1), 3 (T2), 6 (T3), 12 (T4) and 36 hours (T5) after the injection. Clinical and physical variables and cellular and biochemical... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Horse; Synovitis; Lipopolysacharide; TNF-alpha; Lidocaine. |
| Ano: 2004 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352004000300001 |
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