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Lissencephaly in a Pekingese OAK
Shimbo, Genya; Tagawa, Michihito; Oohashi, Eiji; Yanagawa, Masashi; Miyahara, Kazuro.
A 1-year-old neutered male Pekingese was presented for evaluation and further treatment of cluster seizures. The dog had behavioral abnormalities, and a prosencephalic lesion was suspected following neurological examination. The dog showed signs of learning difficulty. Magnetic resonance imaging of the brain revealed a remarkably smooth cerebral cortex with a reduced number of gyri, as well as a cystic lesion associated with the quadrigeminal cistern. A diagnosis of lissencephaly, concurrent with a quadrigeminal cisternal cyst, was made. High-dose and multiple anticonvulsants were necessary to control the seizures. This is the first report of lissencephaly in a Pekingese. © 2017 The Japanese Society of Veterinary Science.
Palavras-chave: Lissencephaly; Magnetic resonance imaging; Pekingese.
Ano: 2017 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4564
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Lissencephaly-pachygyria and cerebellar hypoplasia in a calf Ciência Rural
Santos,Bianca Lemos dos; Damé,Maria Cecília Florisbal; Coelho,Ana Carolina Barreto; Oliveira,Plínio Aguiar; Marcolongo-Pereira,Clairton; Schild,Ana Lucia.
ABSTRACT: A case of lissencephaly-pachygyria and cerebellar hypoplasia diagnosed in a Charolais x Tabapuã calf is described. The calf presented since birth, clinical signs characterized by apathy, prolonged recumbency, tremors of the head and neck, ataxia, hypermetria, difficulty walking, blindness and swelling of the joints of the four limbs. Due to the unfavorable prognosis, the animal was euthanized and necropsied at 34 days of age. At necropsy, a rudimentary development of the brain folds (gyri) and grooves (sulci) was observed, and the cerebellum was hypoplastic. The cut surface of the brain exhibited thickening of the gray matter (pachygyria) in the frontal, parietal, temporal and occipital cortices and narrowing of the white matter. In the organs of...
Tipo: Info:eu-repo/semantics/report Palavras-chave: Lissencephaly; Pachygyria; Cerebellar hypoplasia; Congenital malformation; Cattle.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782016000901622
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