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| Registros recuperados: 95 | |
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| Jiao,Yan; Zhang,Jifei; Yan,Jian; Stuart,John; Gibson,Griffin; Lu,Lu; Willaims,Robert; Wang,Yong Jun; Gu,Weikuan. |
| The aim of this study was to test the hypothesis that hepatic vitamin C (VC) levels in VC deficient mice rescued with high doses of VC supplements still do not reach the optimal levels present in wild-type mice. For this, we used a mouse scurvy model (sfx) in which the L-gulonolactone oxidase gene (Gulo) is deleted. Six age- (6 weeks old) and gender- (female) matched wild-type (WT) and sfx mice (rescued by administering 500 mg of VC/L) were used as the control (WT) and treatment (MT) groups (n = 3 for each group), respectively. Total hepatic RNA was used in triplicate microarray assays for each group. EDGE software was used to identify differentially expressed genes and transcriptomic analysis was used to assess the potential genetic regulation of Gulo... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Gene expression; L-gulonolactone oxidase; Liver; Oxidative stress; Vitamin C. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572011000300004 |
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| Mazurais, David; Ferraresso, Serena; Gatta, Pier Paolo; Desbruyeres, Elisabeth; Severe, Armelle; Corporeau, Charlotte; Claireaux, Guy; Bargelloni, Luca; Zambonino, Jose-luis. |
| Coastal systems could be affected by hypoxic events brought about by global change. These areas are essential nursery habitats for several fish species including the common sole (Solea solea L.). Tolerance of fish to hypoxia depends on species and also on their physiological condition and nutritional status. Indeed, high dietary lipid content has been recently shown to negatively impact the resistance of sole to a severe hypoxic challenge. In order to study the molecular mechanisms involved in the early response to hypoxic stress, the present work examined the hepatic transcriptome in common sole fed diets with low and high lipid content, exposed to severe hypoxia. The activity of AMP-activated protein kinase (AMPK) was also investigated through the... |
| Tipo: Text |
Palavras-chave: Fish; Hypoxia; Nutrition; Liver; Transcriptome; AMPK. |
| Ano: 2014 |
URL: http://archimer.ifremer.fr/doc/00169/28062/26474.pdf |
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| Regost, Christelle; Arzel, Jacqueline; Robin, Jean; Rosenlund, Grethe; Kaushik, Sadasivam. |
| The aim of the study was to investigate the replacement of fish oil by vegetable oils and the effects of a washout with a return to fish oil on growth performances and lipid metabolism. three experimental fish meal-based isonitrogenous (crude protein content: 57.5%) and isolipidic (crude lipid content: 16.5%) diets were formulated containing either 9% of added fish oil (170), soybean oil (SO), or linseed oil (LO). Each diet was distributed to triplicate groups of 25 marketable size turbot (initial body weight of 579 g) grown in seawater at water temperature of 17 T. Fish were fed once a day to visual satiety. At the end of the growth trial, which lasted 13 weeks, all groups of turbot were fed with FO diet for 8 weeks. The growth of turbot was high, but the... |
| Tipo: Text |
Palavras-chave: Lipogenesis; Fatty acids; Liver; Muscle; Body composition; Growth; Vegetable oil; Fish oil; Psetta maxima. |
| Ano: 2003 |
URL: http://archimer.ifremer.fr/doc/2003/publication-375.pdf |
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| Jaffal, Ali; Betoulle, Stephane; Biagianti-risbourg, Sylvie; Terreau, Alexandre; Sanchez, Wilfried; Paris-palacios, Severine. |
| The Kerguelen Islands include various species of freshwater fish such as brown trout (Salmo trutta). These trout are among the most isolated from direct anthropogenic impact worldwide. This study was designed to analyse cadmium (Cd) and copper (Cu) concentrations in the liver of Kerguelen brown trout, and to assess the possible impacts of these metals on hepatic histopathology and oxidative stress parameters (superoxide dismutase and catalase activity and glutathione levels). Trout were caught in the Chateau River, the Studer Lakes and the Ferme Pond, close to the scientific station of the Kerguelen Islands, corresponding to three morphotypes (river, lake and station). Kerguelen trouts' hepatic concentrations of Cd and Cur were similar to those reported in... |
| Tipo: Text |
Palavras-chave: Brown trout; Freshwater; Fish; Sub-Antarctic; Liver; Biomarkers. |
| Ano: 2015 |
URL: https://archimer.ifremer.fr/doc/00499/61109/64571.pdf |
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| Maitre, J; Mercier, L; Dolo, L; Valotaire, Y. |
| In the liver of rainbow trout (Salmo gairdnerii ), vitellogenin (Vg) synthesis is influenced by oestradiol (E sub(2)) which is believed to act through the classical mechanism of steroid hormone action. After binding of the hormone to a soluble specific receptor protein, the oestradiol-receptor complex is translocated to the nucleus, where it interacts with DNA and modulates expression of Vg genes, leading to increased synthesis of specific mRNA and Vg. The authors show here: (i) the presence of specific oestrogen receptors in the cytosol of the male trout liver. (ii) The male liver, offering, an ideal experimental control of "zero" background, the authors followed - in the liver of male trouts - the kinetics of induction of Vg mRNA by hybridization with Vg... |
| Tipo: Text |
Palavras-chave: Salmonidae; Pisces; Proteins; Liver; RNA; Steroids; Biosynthesis; Receptors; Sex hormones; Sexual reproduction. |
| Ano: 1983 |
URL: http://archimer.ifremer.fr/doc/1983/acte-1230.pdf |
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| Panserat, S.; Hortopan, G. A.; Plagnes-juan, E.; Kolditz, C.; Lansard, M.; Skiba-cassy, S.; Esquerre, D.; Geurden, I.; Medale, Francoise; Kaushik, Sadasivam; Corraze, Genevieve. |
| Our objective was to analyse the hepatic transcriptomes of juvenile rainbow trout fed with a plant-based diet. We focused our analysis on the total replacement of fish meal (FM) and fish oil (FO) by a 100% plant-based diet (0% FM, 0% FO). We analysed the postprandial hepatic transcriptomes of rainbow trout fed the two diets 8 h after feeding. Six total hepatic RNAs from each dietary group were hybridised against a trout cDNA microarray (9K). After treatment of the data respecting the standard MIAME (Minimum Information About a Microarray Experiment) protocol, we found that 176 hepatic genes were differentially expressed between fish fed the two diets: 96 and 80 were over-expressed and under-expressed, respectively, in trout fed the plant-based diet. A... |
| Tipo: Text |
Palavras-chave: Rainbow trout; Transcriptome; Metabolism; Liver; Vegetable products; Marine ingredients. |
| Ano: 2009 |
URL: http://archimer.ifremer.fr/doc/2009/publication-6684.pdf |
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| Salin, Karine; Auer, Sonya K.; Rudolf, Agata M.; Anderson, Graeme J.; Selman, Colin; Metcalfe, Neil B.. |
| Standard metabolic rate (SMR) and maximum metabolic rate (MMR) typically vary two-or threefold among conspecifics, with both traits assumed to significantly impact fitness. However, the underlying mechanisms that determine such intraspecific variation are not well understood. We examined the influence of mitochondrial properties on intraspecific variation in SMR and MMR and hypothesized that if SMR supports the cost of maintaining the metabolic machinery required for MMR, then the mitochondrial properties underlying these traits should be shared. Mitochondrial respiratory capacity (leak and phosphorylating respiration) and mitochondrial content (cytochrome c oxidase activity) were determined in the liver and white muscle of brown trout Salmo trutta of... |
| Tipo: Text |
Palavras-chave: Brown trout; Fish; Liver; Oxygen consumption; White muscle. |
| Ano: 2016 |
URL: https://archimer.ifremer.fr/doc/00413/52497/53321.pdf |
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| Nayak B,Satheesha. |
| Liver is the largest gland in the body and rarely shows variations in its lobes and fissures. We studied 55 Formalin-fixed livers for occurrence of abnormal shape, lobes, fissures and position of gall bladder. In 60% of cases the liver was normal. 40% livers showed one or the other variations. Additional lobes were found in 9.09% of cases. Additional fissure was found in 1.81% of cases. Presence of dumbbell shaped caudate lobe and presence of large papillary process was noted in 1.81% cases each. In 1.81% cases the fissure for ligamentum teres was absent or situated on the anterior surface of the liver. In 1.81% of cases each the liver was either extremely long or extremely flat. In 18.18% of the cases, the gall bladder was short and its fundus did not... |
| Tipo: Journal article |
Palavras-chave: Liver; Gall bladder; Variation; Lobe; Fissure; Abnormal. |
| Ano: 2013 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000200051 |
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| Ofusori,David A; Ayoka,Abiodun O; Adeeyo,Olusola A; Adewole,Stephen O. |
| The aim of this study was to substitute costly and hazardous compound- xylene, used as clearing agent, with less costly compounds (mixture of xylene and kerosene) having less toxicity and without compromising the cellular integrity and staining characteristics of the sections. Tissues (liver and kidney) obtained from a presumable healthy adult Wistar rat, were fixed in 10% formol saline, separated in to five groups (A, B, C, D and E) and processed for light microscopic study adopting H & E staining procedure. During the clearing section, groups A, B, C, D and E were respectively cleared in solvent 1 (xylene only), solvent 2 (70ml xylene : 30ml kerosene), solvent 3 (50ml xylene : 50ml kerosene), solvent 4 (30ml xylene : 70ml kerosene) and solvent 5... |
| Tipo: Journal article |
Palavras-chave: Xylene; Kerosene; Clearing agent; Liver; Kidney. |
| Ano: 2009 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000100036 |
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| Ruiz-Picos,R; López-López,E. |
| In aquatic ecosystems, the complex mixture of pollutants may mediate the formation of free radicals and cause oxidative damage to the biota. Yuriria Lake (a Ramsar site in Central Mexico) receives input of wastewater from its tributaries, agricultural runoff, and municipal discharge. We studied the lipid peroxidation (LPO), antioxidant enzymes (superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx), and histopathology of gill and liver of the native fish Goodea atripinnis in Yuriria Lake. Results were compared to a control group of fish cultivated in the laboratory. LPO, SOD, and CAT showed no significant differences compared to controls, but GPx showed greater and significant differences in both tissues. Three class sizes were... |
| Tipo: Journal article |
Palavras-chave: Mexican wetlands; Oxidative stress; Histopathology; Fish health condition; Liver; Gill. |
| Ano: 2012 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000300060 |
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| Pérez,W; Lima,M. |
| The objective of this work is to give a complementary description of the hepatic lobulation, the hepatic ligaments and the omenta of the nutria. Thirty nutrias were studied by gross dissection. The liver of the nutria was divided into six lobules as follows: left lateral, left medial, quadrate, right medial, right lateral, and caudate lobes. The caudate lobe was divided into a papillary and a caudate process. A whole falciform ligament, extending as far as the navel, was found in all animals. This one was the only ligament that contained fat in between its sheets, and it was abundant in the umbilical part. The left triangular ligament had two parts. One of them was attached to the left lateral lobe of the liver and the other one to the left medial lobe.... |
| Tipo: Journal article |
Palavras-chave: Anatomy; Liver; Hepatic ligaments; Omenta. |
| Ano: 2007 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022007000100007 |
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| Pereira,Bruno Fiorelini; Alves,Anderson Luis; Senhorini,José Algusto; Rocha,Rita de Cássia Gimenes de Alcântara; Pitol,Dimítrius Leonardo; Caetano,Flávio Henrique. |
| Currently there is a growing concern, in both population and governments, to identify the effects of substances commonly disposed of into rivers and lakes, on aquatic fauna and flora. Thus the objective of the present study was to verify effects of biodegradable detergents and water from an urban lake on gills and liver of two neotropical fish species of great economic importance, Astyanax altiparanae and Prochilodus lineatus. In order to do so, lipofuscin, also called the ageing pigment, was used as bioindicator. After one and five months of experiment both tissues accumulated this pigment. These data are discussed from physiological points of view, related with lipid peroxidation and mitochondrial damage. |
| Tipo: Journal article |
Palavras-chave: Lipofuscin; Liver; Gill; Prochilodus; Astyanax. |
| Ano: 2014 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022014000300005 |
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| Sandoval,Cristian; Vásquez,Bélgica; Mandarim-de-Lacerda,Carlos; del Sol,Mariano. |
| Prolonged alcohol consumption has consequences on the liver, producing necrotic precipitates and fibrosis, on the pancreas, causing the pancreatic acini to atrophy and destroying insulin-producing cells, and on the central nervous system (CNS), causing the gray and white matter in the frontal lobes of the brain and cerebellum to atrophy. Generally, alcohol is metabolized via oxidative pathways, where the enzymes alcohol dehydrogenase and aldehyde dehydrogenase participate during its metabolization in the liver and CNS, or via non-oxidative pathways during its metabolization in the pancreas. Ethanol metabolism can produce oxidative stress and tissue damage mediated by free radicals, causing morphological and functional alterations in the liver. In the... |
| Tipo: Journal article |
Palavras-chave: Antioxidants; Ethanol; Liver; Pancreas; Central nervous system. |
| Ano: 2017 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022017000300024 |
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| Neves,Renata Heisler; Barros Alencar,Alba Cristina Miranda de; Aguila,Marcia Barbosa; Mandarim-de-Lacerda,Carlos Alberto; Machado-Silva,José Roberto; Gomes,Delir Corrêa. |
| This study evaluated whether a high fat diet (HFC group) induces overweight, hepatic steatosis and plasma lipoproteins level alteration compared to standard chow diet (SC group). Female mice were submitted to each diet over 6 months. Body mass and food intake were evaluated weekly throughout the experiment. Total cholesterol, TG, LDL-c, HDL-c and VLDL-c were analyzed. Mice were sacrificed to remove liver, spleen, heart and intestine. The volume of the organs was determined according to the submersion method. Fixed livers were embedded in paraffin and stained with hematoxylin and eosin and Masson's trichrome. The analysis used a video microscope system and a test-system with 42 test-points. The volume density was estimated for hepatocytes, steatosis and... |
| Tipo: Journal article |
Palavras-chave: Hypercholesterolemia; Experimental model; Mice; Cholesterol; Diet; Liver. |
| Ano: 2006 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022006000500018 |
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| Kosif,Rengin; Yilmaz,Fahri; Evrendilek,Gülsün Akdemir; Diramali,Murat. |
| Aloe Barbadensis, which is a species of Aloe vera, is a popular plant used by the common people and in alternative medicine. This study aimed to analyze the effects of Aloe Barbadensis and soybean oil on liver. For this study Wistar Albino female rats were taken and divided into 3 equal groups; the first group was the control group wherein no treatment was applied, second group in which the dissolved form of A. barbadensis in the soybean oil was applied (25 mg/day), and the third group which only soybean oil was applied (500 mg/day). Biopsy materials were taken from the lobus dexter of the livers of the rats and analyzed with light microscope after the necessary standard processing of histologic slides. Group I demonstrated normal structural... |
| Tipo: Journal article |
Palavras-chave: Aloe barbadensis; Soybean; Rat; Liver; Effect. |
| Ano: 2010 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022010000400019 |
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| Registros recuperados: 95 | |
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