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Peres,P.; Bernardelli,G.F.; Mendes,C.C.; Fischer,S.S.C.P.M.; Servantes,D.M.; Medeiros,W.M.; Carvalho,A.C.. |
Marfan syndrome (MS) is a dominant autosomal disease caused by mutations in chromosome 15, the locus controlling fibrillin 1 synthesis, and may exhibit skeletal, ocular, cardiovascular, and other manifestations. Pulse wave velocity (PWV) is used to measure arterial elasticity and stiffness and is related to the elastic properties of the vascular wall. Since the practice of exercise is limited in MS patients, it was of interest to analyze the acute effect of submaximal exercise on aortic distensibility using PWV and other hemodynamic variables in patients with MS with either mild or no aortic dilatation. PWV and physiological variables were evaluated before and after submaximal exercise in 33 patients with MS and 18 controls. PWV was 8.51 ± 0.58 at rest and... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Exercise; Aortic elasticity; Pulse wave velocity; Marfan syndrome. |
Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000400011 |
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