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Morphine infusions into the rostrolateral periaqueductal gray affect maternal behaviors BJMBR
Moura,L.M.; Canteras,N.S.; Sukikara,M.H.; Felicio,L.F..
It is well established that morphine inhibits maternal behaviors. Previous studies by our group have shown activation of the rostrolateral periaqueductal gray (rlPAG) upon inhibition-intended subcutaneous injections of morphine. In this context, we demonstrated that a single naloxone infusion into the rlPAG, following this opioid-induced inhibition, reactivated maternal behaviors. Since these data were obtained by using peripheral morphine injections, the present study was designed to test whether morphine injected directly into the rlPAG would affect maternal behaviors. Our hypothesis that morphine acting through the rlPAG would disrupt maternal behaviors was confirmed with a local infusion of morphine. The mothers showed shorter latency for locomotor...
Tipo: Info:eu-repo/semantics/article Palavras-chave: PAG; Maternal behaviors; Lactation; Opiate; Active behavior.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000900013
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