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	Provedor de dados Anais da ABC (AABC) (4) Autor BOLZANI,VANDERLAN S. (2) VALLI,MARILIA (2) ANDRICOPULO,ADRIANO D. (1) BARREIRO,ELIEZER J. (1) FERREIRA,LEONARDO G. (1) OLIVA,GLAUCIUS (1) RUSSO,HELENA M. (1) Mais... Palavra-chave Medicinal chemistry (4) Brazilian biodiversity (2) Database (2) Natural products (2) Cancer (1) Ligand-based drug design (1) Natural biophores as drug scaffolds (1) Natural products as lead-compounds to drugs (1) Neglected tropical diseases (1) New drugs candidates (1) Structure-based drug design (1) Mais... Tipo do documento Info:eu-repo/semantics/article (4) Ano 2019 (2) 2018 (2) País Brazil (4) Idioma Inglês (4)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 4 Primeira ... 1 ... Última Natural Products: Perspectives and Challenges for use of Brazilian Plant Species in the Bioeconomy Anais da ABC (AABC) VALLI,MARILIA; BOLZANI,VANDERLAN S.. Abstract: The development of our society has been based on the use of biodiversity, especially for nutrition, medicines and beauty. Brazil is the nation with the largest biodiversity in the world, with a rich chemical diversity, which is a potential source for bioeconomy. Considering the chemical and biological diversity of the Brazilian territory, we would like to highlight the value of secondary metabolites from Brazilian biodiversity with potential application for new products and technologies and the importance of scientific programs to support the sustainable use of biodiversity. Tipo: Info:eu-repo/semantics/article Palavras-chave: Brazilian biodiversity; Natural products; Database; Medicinal chemistry. Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000600402 The potential contribution of the natural products from Brazilian biodiversity to bioeconomy Anais da ABC (AABC) VALLI,MARILIA; RUSSO,HELENA M.; BOLZANI,VANDERLAN S.. ABSTRACT The development of our society has been based on the use of biodiversity, especially for medicines and nutrition. Brazil is the nation with the largest biodiversity in the world accounting for more than 15% of all living species. The devastation of biodiversity in Brazil is critical and may not only cause the loss of species and genes that encode enzymes involved in the complex metabolism of organisms, but also the loss of a rich chemical diversity, which is a potential source for bioeconomy based on natural products and new synthetic derivatives. Bioeconomy focus on the use of bio-based products, instead of fossil-based ones and could address some of the important challenges faced by society. Considering the chemical and biological diversity of... Tipo: Info:eu-repo/semantics/article Palavras-chave: Brazilian biodiversity; Natural products; Medicinal chemistry; Database. Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000200763 What is hidden in the biodiversity? The role of natural products and medicinal chemistry in the drug discovery process Anais da ABC (AABC) BARREIRO,ELIEZER J.. Abstract Abstract: This manuscript describes the role of natural products in the process of drug discovery. In fact, several different natural compounds have been used as inspiration to develop new drugs. Some relevant examples are presented in chronological order. Tipo: Info:eu-repo/semantics/article Palavras-chave: Medicinal chemistry; Natural biophores as drug scaffolds; Natural products as lead-compounds to drugs; New drugs candidates. Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000600401 From Medicinal Chemistry to Human Health: Current Approaches to Drug Discovery for Cancer and Neglected Tropical Diseases Anais da ABC (AABC) FERREIRA,LEONARDO G.; OLIVA,GLAUCIUS; ANDRICOPULO,ADRIANO D.. ABSTRACT Scientific and technological breakthroughs have compelled the current players in drug discovery to increasingly incorporate knowledge-based approaches. This evolving paradigm, which has its roots attached to the recent advances in medicinal chemistry, molecular and structural biology, has unprecedentedly demanded the development of up-to-date computational approaches, such as bio- and chemo-informatics. These tools have been pivotal to catalyzing the ever-increasing amount of data generated by the molecular sciences, and to converting the data into insightful guidelines for use in the research pipeline. As a result, ligand- and structure-based drug design have emerged as key pathways to address the pharmaceutical industry’s striking demands for... Tipo: Info:eu-repo/semantics/article Palavras-chave: Medicinal chemistry; Ligand-based drug design; Structure-based drug design; Cancer; Neglected tropical diseases. Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000200645 Registros recuperados: 4 Primeira ... 1 ... Última

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