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	Provedor de dados BJMBR (2) Anais da ABC (AABC) (1) J. Venom. Anim. Toxins incl. Trop. Dis. (1) Autor Arumugam,M (1) Balasubramaniam,T (1) Borges,A.C.R. (1) Dalle Lucca,J.J. (1) Dalle Lucca,S.L.D. (1) Hill,Reghan J. (1) Ihara,S.S.M. (1) Karthikeyan,S (1) Moura,A.S. (1) Paiva,T.B. (1) Prasad,N Rajendra (1) Rajeshkumar,RK (1) Velpandian,T (1) Vennila,R (1) Mais... Palavra-chave Membrane potential (4) Bradykinin (1) Calcium (1) Electrodiffusion (1) Electrokinetic phenomena (1) Hydrogel-colloid composites (1) Marine organisms (1) Microhydrodynamics (1) Oxidative stress (1) Pancreatic beta cell (1) ROS (1) Renovascular hypertension (1) Restenosis (1) SHR (1) Smooth muscle cell (1) Soft composite materials (1) Stingray (1) Streaming potential (1) Venom (1) Mais... Tipo do documento Info:eu-repo/semantics/article (3) Info:eu-repo/semantics/other (1) Ano 2015 (1) 2010 (1) 2000 (2) País Brazil (4) Idioma Inglês (4)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 4 Primeira ... 1 ... Última Antiproliferative activity of marine stingray Dasyatis sephenvenom on human cervical carcinoma cell line J. Venom. Anim. Toxins incl. Trop. Dis. Rajeshkumar,RK; Vennila,R; Karthikeyan,S; Prasad,N Rajendra; Arumugam,M; Velpandian,T; Balasubramaniam,T. AbstractBackgroundVenoms comprise mixtures of numerous bioactive compounds that have a wide range of pharmacologic actions. Toxins from venomous animals have attracted the attention of researchers because of their affinity for primary sites responsible for lethality and their efficacy at extremely low concentrations. The venoms of marine stingrays have not been extensively studied and limited data is available on them. The present study aims to evaluate the antiproliferative and biochemical properties of the venom obtained from a species of marine stingray (Dasyatis sephen) on human cervical cancer cell line HeLa.MethodsThe antiproliferative effect of D. sephen venom was determined by MTT assay, and the oxidative stress was determined by lipid peroxidation... Tipo: Info:eu-repo/semantics/article Palavras-chave: Marine organisms; Membrane potential; Oxidative stress; ROS; Stingray; Venom. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992015000100345 Steady electrodiffusion in hydrogel-colloid composites: macroscale properties from microscale electrokinetics Anais da ABC (AABC) Hill,Reghan J.. A rigorous microscale electrokinetic model for hydrogel-colloid composites is adopted to compute macroscale profiles of electrolyte concentration, electrostatic potential, and hydrostatic pressure across membranes that separate electrolytes with different concentrations. The membranes are uncharged polymeric hydrogels in which charged spherical colloidal particles are immobilized and randomly dispersed with a low solid volume fraction. Bulk membrane characteristics and performance are calculated from a continuum microscale electrokinetic model (Hill 2006b, c). The computations undertaken in this paper quantify the streaming and membrane potentials. For the membrane potential, increasing the volume fraction of negatively charged inclusions decreases the... Tipo: Info:eu-repo/semantics/article Palavras-chave: Electrodiffusion; Electrokinetic phenomena; Hydrogel-colloid composites; Membrane potential; Microhydrodynamics; Soft composite materials; Streaming potential. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652010000100007 Bradykinin enhances membrane electrical activity of pancreatic beta cells in the presence of low glucose concentrations BJMBR Moura,A.S.. In most of cells bradykinin (BK) induces intracellular calcium mobilization. In pancreatic beta cells intracellular calcium is a major signal for insulin secretion. In these cells, glucose metabolism yields intracellular ATP which blocks membrane potassium channels. The membrane depolarizes, voltage-dependent Ca2+ channels are activated and the intracellular calcium load allows insulin secretion. Repolarization occurs due to activation of the Ca2+-dependent K+ channel. The insulin secretion depends on the integrity of this oscillatory process (bursts). Therefore, we decided to determine whether BK (100 nM) induces bursts in the presence of a non-stimulatory glucose concentration (5.6 mM). During continuous membrane voltage recording, our results showed... Tipo: Info:eu-repo/semantics/other Palavras-chave: Membrane potential; Pancreatic beta cell; Bradykinin; Calcium. Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000900016 Abnormal proliferative response of the carotid artery of spontaneously hypertensive rats after angioplasty may be related to the depolarized state of its smooth muscle cells BJMBR Dalle Lucca,S.L.D.; Dalle Lucca,J.J.; Borges,A.C.R.; Ihara,S.S.M.; Paiva,T.B.. Hypertension is one of the major precursors of atherosclerotic vascular disease, and vascular smooth muscle abnormal cell replication is a key feature of plaque formation. The present study was conducted to examine the relationship between hypertension and smooth muscle cell proliferation after balloon injury and to correlate neointima formation with resting membrane potential of uninjured smooth muscle cells, since it has been suggested that altered vascular function in hypertension may be related to the resetting of the resting membrane potential in spontaneously hypertensive rats (SHR). Neointima formation was induced by balloon injury to the carotid arteries of SHR and renovascular hypertensive rats (1K-1C), as well as in their normotensive controls,... Tipo: Info:eu-repo/semantics/article Palavras-chave: SHR; Renovascular hypertension; Restenosis; Smooth muscle cell; Membrane potential. Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000800008 Registros recuperados: 4 Primeira ... 1 ... Última

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