|
|
|
|
|
| Silva, Geysa Janne Sousa; Santos, Fabelina Karollyne Silva dos; Marques, Márcia Maria Mendes; Peron, Ana Paula. |
| This study aimed to evaluate the cytotoxicity and genotoxicity and determine the LC50 concentration of powdered infant formulas widely marketed in South American countries. To this, milk samples, called as A, B, C and D, were analyzed in root meristem cells of Allium cepa, at concentrations of 0.075; 0.15 and 0.30 g mL-1, for 24 and 48 hours; and through cell viability in culture of normal line cells, via MTT test, for 24 hours, in the concentrations 0.018; 0.0375; 0.075 and 0.15 g mL-1. In A. cepa, all dairy products in the three concentrations caused significant inhibition of cell division in the meristems within the first 24 hours of exposure. In the in vitro evaluation, all milk formulas at 0.15 g mL-1, as well as milk A at a concentration of 0.037 g... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Infant formula; Cell division; Meristematic tissue; Cell viability; LC50. |
| Ano: 2020 |
URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/46856 |
| |
|
|
| CARVALHO,Brenda de Lima; SALES,Ila Monize Sousa; PERON,Ana Paula. |
| Abstract This study evaluated the action at the cellular level of long life whole milk, full type of six renowned companies operating in the Brazilian market, as well as in other South American countries. The evaluation was performed using root meristem cells of Allium cepa L., at exposure times 24 and 48 hours, directly in milk products marketed. The results indicated that all the milk samples reduced root meristem cell proliferation, proving, in this study, a significant cytotoxic effect. Still, exposure to milk resulted in a significant frequency of mitotic spindle changes in meristem cells, characterizing these foods as genotoxic and mutagenic under the study conditions. It can be concluded that the long life milk samples caused significant genetic... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Ultra-pasteurized milk; Cell division; Mitotic spindle alterations; Meristematic tissue. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612017000200275 |
| |
|
|
|
