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Registros recuperados: 5
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Protease Inhibitor and Metabolic Alteration International Journal of Morphology
Cavenaghi,F. M; Bataglion,C. A. N; Paula,P. C; Motta,A. C. F; Komesu,M. C.
Protease inhibitors (PIs), part of HAART (Highly Active Antiretroviral Therap) are selective, competitive inhibitors of protease, a crucial enzyme to viral maturation, infection and replication. A lipodystrophic syndrome has been reported in individuals treated with HAART, and associated to hyperglycemia, hypercholesterolemia, hypertrigliceridemia, hyperlipidemia, hypertension and hypreinsulinemia. The HAART-associated metabolic abnormalities were first associated with protease inhibitors, Ritonavir mostly, but the mechamisns that underlie these metabolic alterations are to date, not completely understood. Since PIs are candidate to be the drug of choice for other diseases treatment, such as the Hepatitis C, malaria and some types of cancer, it seems to be...
Tipo: Journal article Palavras-chave: Protease inhibitors; Dyslipidemia; Metabolic disorders.
Ano: 2012 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000200014
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Pendulous Crop in Broilers Rev. Bras. Ciênc. Avic.
Ebling,PD; Pontalti,GC; Villanueva,AP; Ribeiro,AML.
ABSTRACTPendulous crop is a physiological disorder, which etiology is still unknown and it is characterized by abnormal dilation of the crop of poultry. This article aims at reporting a case of high incidence of pendulous crop in male and female broilers Cobb 500, as well as to discuss its possible causes and consequences. In an experiment with broilers performed at the experimental facilities of Laboratório de Ensino Zootécnico of UFRGS, a high incidence (9.5%) of pendulous crop was observed. Genetic predisposition is the most frequently documented and accepted cause of that condition. Despite presenting the same live weight as normal broilers, birds with pendulous crop had lower carcass weight due to dehydration and malnourishment, and should be culled...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Metabolic disorders; Genetic improvement; Feed intake voracity..
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2015000300395
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Scientific progress in ruminant production in the 1st decade of the XXI century R. Bras. Zootec.
Santos,Geraldo Tadeu dos; Silva-Kazama,Daniele Cristina da; Kazama,Ricardo; Petit,Helene V..
Scientific advances in nutrition of dairy cows in the first decade of the XXI century have occurred. This paper will review the most common additives fed to transition cows to decrease the incidence of metabolic disorders, which will be discussed separately with emphasis on their mechanisms of action, utilization and efficiency. Some changes on protein in the 2001 updated version of the Nutrient Requirements of Dairy Cattle to reach better precision of the nitrogen and amino acid requirements of lactating cows also are presented. Many of the advances in nutritional manipulation of milk fat concentration are related to fat supplementation, then the relationship between the action of rumen microbes on biohydrogenation of dietary polyunsaturated fatty acids...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Additives; Biohydrogenation; CLA; Lipids; Metabolic disorders; Protein.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982010001300052
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Nutrition, microbiota, and endotoxin-related diseases in dairy cows R. Bras. Zootec.
Ametaj,Burim N.; Zebeli,Qendrim; Iqbal,Summera.
In this review article we present an overall summary of the role that high-grain/low forage diets have on rumen composition of microbiota and how changes in the diet affect the release of bacterial cell wall components that are toxic to the host. One of these toxic compounds is lipopolysaccharide or endotoxin, a component of the outer membrane of all Gram-negative bacteria. Moreover, data are provided that support the concept that endotoxin translocates into the blood circulation and show that rumen endotoxin is associated with multiple perturbations of blood variables related to carbohydrate, lipid, and mineral metabolism. In addition, endotoxin induces a general, nonspecific immune response known as acute phase response. We also pinpoint the fact that...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Dairy cow; Endotoxin; Metabolic disorders; Nutritional immunology.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982010001300048
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Endocrine and metabolic disorders in HTLV-1 infected patients BJID
Alves,Cresio; Dourado,Luciano.
Human T-cell leukemia virus type 1 (HTLV-1) infection is endemic in Japan and several countries in South America, Caribbean and Africa. Endocrine and metabolic disorders have been variably reported to be associated with human T-cell leukemia virus type 1 (HTLV-1) infection. Therefore, the aim of this article was to critically evaluate the current knowledge of the endocrine and metabolic disorders associated with HTLV-1 infection. The literature search used PubMed, Web of Science, and LILACS databases in the past 10 years, utilizing, in various combinations, the following keywords: HTLV-1, adult T-cell leukemia, diabetes mellitus, GLUT-1, osteoporosis, hypercalcemia, autoimmune thyroid disorders, diabetes insipidus, inappropriate antidiuretic hormone...
Tipo: Info:eu-repo/semantics/article Palavras-chave: HTLV-1; Adult T-cell leukemia; Endocrine disorders; Metabolic disorders.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000600011
Registros recuperados: 5
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