|
|
|
| Registros recuperados: 37 | |
|
| |
|
|
| LIMA,LUÍS M.T.R.. |
| ABSTRACT Type 2 diabetes mellitus (T2DM) is increasing in prevalence worldwide, and those non-diagnosed or misdiagnosed comprise a significant group compared to those diagnosed. Accumulated scientific evidence indicate that the current diagnostic markers (fasting glycemia, 2h glycemia after an oral glucose load and HbA1c) are indeed late diagnostic criteria when considering the incidence of diabetes-related complications and comorbidities, which are also at high risk in some groups among normoglycemic individuals. Additionally, the earlier identification of future risk of diabetes is desirable since it would allow better adherence to preventive actions such as lifestyle intervention, ultimately avoiding complications and minimizing the economic... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Diabetes; Diagnosis; Insulin; Subclinical diabetes; Metabolic syndrome. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000200591 |
| |
|
| |
|
|
| Laskoski,L. M.; Dittrich,R. Locatelli; Valadão,C. A. A; Castro,M. L.; Araujo,F. F.; Silva,J. R.; Basso,F. Z.; Dornbusch,P. T.; Deconto,I.; Sousa,R. S.. |
| ABSTRACTLaminitis in horses is often associated with endocrine disorders, especially the pituitary pars intermedia dysfunction (PPID) in older animals. Morphologic exams of the laminar tissue of the hoof were performed in two horses with suspected PPID, with no clinical signs of laminitis. Changes compatible with laminitis of endocrine origin were observed, such as rounding of the nuclei of the basal cells, thinning and stretching of the secondary epidermal laminae and tissue proliferation. PPID horses with no clinical signs of laminitis may be affected by lesions of the laminar tissue of the hoof that compromise the integrity of the dermal-epidermal junction and may develop clinical symptoms of the disease. It has been suggested that the development stage... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Laminitis; Metabolic syndrome; Cushing's syndrome; Endocrine disorders; Pituitary adenoma. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352015000501226 |
| |
|
|
| Urquiaga,Inés; D'Acuna,Sonia; Pérez,Druso; Dicenta,Sara; Echeverria,Guadalupe; Rigotti,Attilio; Leighton,Federico. |
| BACKGROUND: The Mediterranean diet is a healthy diet with positive scientific evidence of preventing chronic diseases. Bioactive components support the healthy properties of the Mediterranean diet. Antioxidants and fiber, two components of the Mediterranean diet, are key functional nutrients for healthy eating and nutrition. Wine grape pomace is a rich source of these dietary constituents and may be beneficial for human health. Our hypothesis was that the intake of red wine grape pomace flour (WGPF) prepared from red wine grapes (Cabernet Sauvignon variety) reduced the metabolic syndrome in humans. To evaluate the effect of WGPF on components of metabolic syndrome we design a 16-week longitudinal intervention study. Thirty-eight males, 30-65 years of age,... |
| Tipo: Journal article |
Palavras-chave: Antioxidant; Dietary intervention; Fiber; Metabolic syndrome; Oxidative stress; Wine grape pomace. |
| Ano: 2015 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602015000100049 |
| |
|
|
| Iturriaga,Rodrigo; Del Rio,Rodrigo; Idiaquez,Juan; Somers,Virend K.. |
| The carotid body (CB) is the main peripheral chemoreceptor that senses the arterial PO2, PCO2 and pH. In response to hypoxemia, hypercapnia and acidosis, carotid chemosensory discharge elicits reflex respiratory, autonomic and cardiovascular adjustments. The classical construct considers the CB as the main peripheral oxygen sensor, triggering reflex physiological responses to acute hypoxemia and facilitating the ventilatory acclimation to chronic hypoxemia at high altitude. However, a growing body of experimental evidence supports the novel concept that an abnormally enhanced CB chemosensory input to the brainstem contributes to overactivation of the sympathetic nervous system, and consequent pathology. Indeed, the CB has been implicated in several... |
| Tipo: Journal article |
Palavras-chave: Autonomic dysfunction; Carotid body; Heart failure; Metabolic syndrome; Obstructive sleep apnea; Sympathetic activation. |
| Ano: 2016 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602016000100013 |
| |
|
| |
|
|
| Hernández-Salinas,Romina; Decap,Valerie; Leguina,Alberto; Cáceres,Patricio; Perez,Druso; Urquiaga,Ines; Iturriaga,Rodrigo; Velarde,Victoria. |
| BACKGROUND: Metabolic syndrome is a growing worldwide health problem. We evaluated the effects of wine grape powder (WGP), rich in antioxidants and fiber, in a rat model of metabolic syndrome induced by a high fructose diet. We tested whether WGP supplementation may prevent glucose intolerance and decrease oxidative stress in rats fed with a high fructose diet. METHODS: Male Sprague-Dawley rats weighing 180 g were divided into four groups according to their feeding protocols. Rats were fed with control diet (C), control plus 20 % WGP (C + WGP), 50 % high fructose (HF) or 50 % fructose plus 20 % WGP (HF + WGP) for 16 weeks. Blood glucose, insulin and triglycerides, weight, and arterial blood pressure were measured. Homeostasis model assessment (HOMA) index... |
| Tipo: Journal article |
Palavras-chave: Insulin resistance; Oxidative stress; Metabolic syndrome; Wine grape powder. |
| Ano: 2015 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602015000100053 |
| |
|
|
| Anjos,Heloisa Nakai Kwabara dos; Toledo,Max Jean de Ornelas; Mota,Lúcio Tadeu; Previdelli,Isolde Terezinha Santos; Anjos,Adriano Félix dos; Saruhashi,Tiago Ribeiro; Carrara,Márcia Aparecida; Batista,Márcia Regina. |
| The aim of this work was to evaluate the prevalence of metabolic syndrome, diabetes mellitus, and obesity among a Brazilian indigenous population. A cross-sectional study was carried out in 2008 among Kaingang native Americans from the central region of the state of Paraná, Brazil. Eighty two of the inhabitants aged 15 or older were selected. Height, weight, blood pressure, waistline circumference, and hip circumference were measured. After fasting, the blood was collected for the measurement of glucose, HDL cholesterol, triglyceride, total cholesterol, AI and B apolipoprotein, and hemoglobin. The prevalences found were: fasting hyperglycemia (9.8%), hypercholesterolemia (4.9%), reduced HDL cholesterol (13.4%), hypertriglyceridemia (11%), abdominal obesity... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Metabolic syndrome; Health of indigenous peoples; Brazilian native Americans; Kaingang. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000100011 |
| |
|
|
| Didek,Daiane; Cordeiro,Maiara Mikuska; Xavier,João Lucas de Paula; Ribeiro,Paulo Roberto; Rentz,Thiago; Franco,Gilson Cesar Nobre; Kanunfre,Carla Cristine; Emilio,Henriette Rosa de Oliveira; Scomparin,Dionízia Xavier. |
| Abstract The objective of this study was to evaluate the effect of liraglutide, an analog of glucagon-like peptide-1 (GLP-1) in association with physical exercise, on the metabolic and biochemical parameters of rats induced to obesity with a cafeteria diet. Male Wistar rats, aged 21 days, were randomly divided into: Controls (CON) receiving standard feed and water ad libitum; and obese (OBESE) receiving cafeteria diet ad libitum, added to the standard diet. Groups were then subdivided into: Liraglutide animals that received subcutaneous injections of liraglutide from 80 to 90 days of life; exercised (EXE) animals submitted to swimming sessions, three days a week (15 min); and liraglutide + EXE animals that received liraglutide in association with physical... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Obesity; Liraglutide; GLP-1; Metabolic syndrome; Exercise. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132019000100305 |
| |
|
|
| Akl,Lívia D.; Valadares,Ana L.R.; Moraes,Monica Jacques de; Pinto-Neto,Aarão M.; Lagrutta,Bianca; Costa-Paiva,Lúcia. |
| ABSTRACT Objectives: To determine the prevalence of metabolic syndrome (MetS) and its associated factors in a group of HIV-infected middle-aged women. Methods: Cross-sectional study including 273 HIV-infected climacteric women of 40-60 years of age under care in two HIV outpatient reference centers in Brazil. Metabolic syndrome diagnosis was based on 2006 International Diabetes Federation criteria. Sociodemographic, clinical and behavioral factors were evaluated as well as HIV infection-related parameters. Results: Mean age was 47.7 years; 59.1% of women were premenopausal, 91% were on antiretroviral therapy. Current CD4 count was >500 cells/mm3 in 61.7%, current viral load undetectable in 76.9% of women, and a quarter had previous diagnosis of aids.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Metabolic syndrome; Menopause; HIV; Protease inhibitors. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702017000300263 |
| |
|
|
| Cahn,P; Leite,O; Rosales,A; Cabello,R; Alvarez,CA; Seas,C; Carcamo,C; Cure-Bolt,N; L'Italien,Gp; Mantilla,P; Deibis,L; Zala,C; Suffert,T. |
| OBJECTIVE: Determine the prevalence of metabolic abnormalities (MA) and estimate the 10-year risk for cardiovascular disease (CVD) among Latin American HIV-infected patients receiving highly active anti-retroviral therapy (HAART). METHODS: A cohort study to evaluate MA and treatment practices to reduce CVD has been conducted in seven Latin American countries. Adult HIV-infected patients with at least one month of HAART were enrolled. Baseline data are presented in this analysis. RESULTS: A total of 4,010 patients were enrolled. Mean age (SD) was 41.9 (10) years; median duration of HAART was 35 (IQR: 10-51) months, 44% received protease inhibitors. The prevalence of dyslipidemia and metabolic syndrome was 80.2% and 20.2%, respectively. The overall 10-year... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: HAART; HIV; Metabolic parameters; Cardiovascular risk factors; Metabolic syndrome; Dyslipidemia. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000200008 |
| |
|
|
| Gronner,M.F.; Bosi,P.L.; Carvalho,A.M.; Casale,G.; Contrera,D.; Pereira,M.A.; Diogo,T.M.; Torquato,M.T.C.G.; Souza,G.M.D.; Oishi,J.; Leal,A.M.O.. |
| The present study estimated the prevalence of metabolic syndrome (MS) according to the criteria established by the National Cholesterol Education Program-Adult Treatment Panel III (NCEP-ATPIII) and the International Diabetes Federation (IDF) and analyzed the contribution of social factors in an adult urban population in the Southeastern region of Brazil. The sample plan was based on multistage probability sampling according to family head income and educational level. A random sample of 1116 subjects aged 30 to 79 years was studied. Participants answered a questionnaire about socio-demographic variables and medical history. Fasting capillary glucose (FCG), total cholesterol, high-density lipoprotein cholesterol (HDL-C), and triglycerides were determined... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Metabolic syndrome; Prevalence; Brazil; Diabetes. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000700016 |
| |
|
|
| Barbieri,M.A.; Bettiol,H.; Silva,A.A.M.; Cardoso,V.C.; Simões,V.M.F.; Gutierrez,M.R.P.; Castro,J.A.S.; Vianna,E.S.O.; Foss,M.C.; Dos Santos,J.E.; Queiroz,R.G.P.. |
| The increase in non-communicable chronic diseases of adults is due to demographic changes and changes in the risk factors related to physical activity, smoking habits and nutrition. We describe the methodology for the evaluation of persons at 23/25 years of age of a cohort of individuals born in Ribeirão Preto in 1978/79. We present their socioeconomic characteristics and the profile of some risk factors for chronic diseases. A total of 2063 participants were evaluated by means of blood collection, standardized questionnaires, anthropometric and blood pressure measurements, and methacholine bronchoprovocation tests. The sexes were compared by the chi-square test, with alpha = 0.05. Obesity was similar among men and women (12.8 and 11.1%); overweight was... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Non-communicable chronic diseases of adults; Metabolic syndrome; Obesity; Arterial hypertension Asthma; Dyslipidemia. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000800007 |
| |
|
|
| Almeida-Pititto,B.; Gimeno,S.G.A.; Freire,R.D.; Ribeiro-Filho,F.F.; Ferreira,S.R.G.. |
| We evaluated the relationship of leptin with hypertension adjusted for body mass index (BMI) and/or waist circumference in a population of Japanese-Brazilian women aged > or = 30 years with centrally distributed adiposity. After excluding diabetic subjects, the study subjects - who participated in a population-based study on the prevalence of metabolic syndrome - showed prevalence rates of obesity (BMI > or = 25 kg/m²) and central adiposity (waist > or = 80 cm) of 32.0 and 37.8%, respectively. The hypertensive group (N = 162) was older, had higher BMI (24.9 ± 4.2 vs 23.3 ± 3.4 kg/m², P < 0.001), waist circumference (81.1 ± 10.1 vs 76.3 ± 8.2 cm, P < 0.001) and insulin levels (8.0 ± 6.2 vs 7.1 ± 4.9 µU/mL, P < 0.05) than the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hypertension; Body fat distribution; Insulin; Leptin; Centrally obese; Metabolic syndrome. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000100012 |
| |
|
|
| Martins,R.C.; Andersen,M.L.; Tufik,S.. |
| Type 2 diabetes mellitus is a systemic disease characterized by intolerance to glucose and peripheral resistance to insulin. This endocrine disease affects fundamental mechanisms of the central nervous system and jeopardizes the balance of vital functions such as the cardiovascular and circadian rhythm. The increased prevalence of metabolic disorders in our society is aggravated by endemic voluntary postponement of bedtime and by the current sedentary lifestyle, leading to epidemic proportions of obese people. Diabetes and chronic loss of sleep share the fact that both affect millions and one is detrimental to the other. Indeed, sleep deficits have marked modulatory effects on glucose metabolism and insulin sensitivity and foster metabolic syndrome that... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Diabetes; Metabolic syndrome; Obesity; Apnea; Sleep. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008000300001 |
| |
|
|
| Mourão-Júnior,C.A.; Sá,J.R.; Guedes,O.M.S.; Dib,S.A.. |
| Fifty-seven type 2 diabetic patients with metabolic syndrome and on insulin were assessed by a paired analysis before and 6 months after addition of metformin as combination therapy to evaluate the impact of the association on glycemic control, blood pressure, and lipid profile. This was a historical cohort study in which the files of type 2 diabetic patients with metabolic syndrome on insulin were reviewed. The body mass index (BMI), waist circumference, lipid profile, A1C level, fasting blood glucose level, daily dose of NPH insulin, systolic blood pressure, and diastolic blood pressure were assessed in each patient before the start of metformin and 6 months after the initiation of combination therapy. Glycemic control significantly improved (P <... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Type 2 diabetes mellitus; Metabolic syndrome; Metformin; Blood pressure; Cholesterol; Triglycerides. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000400009 |
| |
|
|
| Monteiro,C.M.C.; Pinheiro,L.F.; Izar,M.C.; Barros,S.W.; Vasco,M.B.; Fischer,S.M.; Povoa,R.M.; Brandão,S.A.; Santos,A.O.; Oliveira,L.; Carvalho,A.C.; Fonseca,F.A.H.. |
| Patients with metabolic syndrome are at high-risk for development of atherosclerosis and cardiovascular events. The objective of this study was to examine the major determinants of coronary disease severity, including those coronary risk factors associated with metabolic syndrome, during the early period after an acute coronary episode. We tested the hypothesis that inflammatory markers, especially highly sensitive C-reactive protein (hsCRP), are related to coronary atherosclerosis, in addition to traditional coronary risk factors. Subjects of both genders aged 30 to 75 years (N = 116) were prospectively included if they had suffered a recent acute coronary syndrome (acute myocardial infarction or unstable angina pectoris requiring hospitalization) and if... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Metabolic syndrome; Acute coronary syndrome; C-reactive protein; Gender; Gensini score. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000300012 |
| |
|
|
| Simão,A.N.C.; Lozovoy,M.A.B.; Simão,T.N.C.; Venturini,D.; Barbosa,D.S.; Dichi,J.B.; Matsuo,T.; Cecchini,R.; Dichi,I.. |
| Metabolic syndrome (MS) is a multifactorial disease involving inflammatory activity and endothelial dysfunction. The aim of the present study was to evaluate the relationship between the changes in lipoperoxidation, in immunological and biochemical parameters and nitric oxide metabolite (NOx) levels in MS patients. Fifty patients with MS (4 males/46 females) and 50 controls (3 males/47 females) were studied. Compared to control (Mann-Whitney test), MS patients presented higher serum levels (P < 0.05) of fibrinogen: 314 (185-489) vs 262 (188-314) mg/dL, C-reactive protein (CRP): 7.80 (1.10-46.50) vs 0.70 (0.16-5.20) mg/dL, interleukin-6: 3.96 (3.04-28.18) vs 3.33 (2.55-9.63) pg/mL, uric acid: 5.45 (3.15-9.65) vs 3.81 (2.70-5.90) mg/dL, and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Metabolic syndrome; Uric acid; Inflammation; Adiponectin; Nitric oxide; Lipoperoxidation. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000700015 |
| |
|
|
| Marques,C.M.M.; Motta,V.F.; Torres,T.S.; Aguila,M.B.; Mandarim-de-Lacerda,C.A.. |
| C57BL/6 mice develop signs and symptoms comparable, in part, to the human metabolic syndrome. The objective of the present study was to evaluate the effects of exercise training on carbohydrate metabolism, lipid profile, visceral adiposity, pancreatic islet alterations, and nonalcoholic fatty liver disease in C57BL/6 mice. Animals were fed one of two diets during an 8-week period: standard (SC, N = 12) or very high-fat (HF, N = 24) chow. An exercise training protocol (treadmill) was then established and mice were divided into SC and HF sedentary (SC-Sed, HF-Sed), exercised groups (SC-Ex, HF-Ex), or switched from HF to SC (HF/SC-Sed and HF/SC-Ex). HF/HF-Sed mice had the greatest body mass (65% more than SC/SC-Sed; P < 0.0001), and exercise reduced it by... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Obesity; Lipid metabolism; Metabolic syndrome; Aerobic training; Fatty liver; Stereology. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000500008 |
| |
| Registros recuperados: 37 | |
|
|
|
