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Carbapenem-resistant Pseudomonas aeruginosa: association with virulence genes and biofilm formation BJM
Gonçalves,Iara Rossi; Dantas,Raquel Cristina Cavalcanti; Ferreira,Melina Lorraine; Batistão,Deivid William da Fonseca; Gontijo-Filho,Paulo Pinto; Ribas,Rosineide Marques.
Abstract Pseudomonas aeruginosa is an opportunistic pathogen that causes frequently nosocomial infections, currently becoming more difficult to treat due to the various resistance mechanisms and different virulence factors. The purpose of this study was to determine the risk factors independently associated with the development of bacteremia by carbapenem-resistant P. aeruginosa, the frequency of virulence genes in metallo-β-lactamases producers and to evaluate their ability to produce biofilm. We conducted a case–control study in the Uberlândia Federal University – Hospital Clinic, Brazil. Polymerase Chain Reaction was performed for metallo-β-lactamases and virulence genes. Adhesion and biofilm assays were done by quantitative tests. Among the 157 strains...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Pseudomonas aeruginosa; Resistance; Metallo-β-lactamases; Virulence; Biofilm.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822017000200211
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Detection of extended spectrum beta lactamases, ampc beta lactamases and metallobetalactamases in clinical isolates of ceftazidime resistant Pseudomonas Aeruginosa BJM
Umadevi,Sivaraman; Joseph,Noyal M; Kumari,Kandha; Easow,Joshy M; Kumar,Shailesh; Stephen,Selvaraj; Srirangaraj,Sreenivasan; Raj,Sruthi.
We studied the prevalence of ceftazidime resistance in Pseudomonas aeruginosa and the rates of extended-spectrum β-lactamase (ESBL), AmpC β-lactamase (AmpC) and metallo-β-lactamase (MBL) production among the ceftazidime resistant Pseudomonas aeruginosa. A very high rate of MBL production was observed, which suggested it to be an important contributing factor for ceftazidime resistance among Pseudomonas aeruginosa.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Extended-spectrum β-lactamases; AmpC; Metallo-β-lactamases; Ceftazidime resistance; Pseudomonas aeruginosa.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822011000400006
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