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| Silva,Mariana Beatriz Scabora da; Ferreira,Aline de Assis; Habr,Soraya Ferreira; Bernardi,Maria Martha. |
| This paper is focused in some aspects of maternal exposure to misoprostol during perinatal period, and the abortive and teratogenesis effects on the fetus. The causes of malformations were revised, taking into account chemical, physical and environmental factors as well as the interaction between them. There are evidences that the practice of abortion tripled in Southern and Northeastern Brazil in 15 years, and one of the most frequent forms of abortion is through the use of misoprostol. In Brazil, 1991, 288,700 women were hospitalized as a consequence of complications induced by abortion attempt with this medicine. This fact resulted in the ban of misoprostol across our country, by Decree 344/98 determined by the Health Ministry. The use of misoprostol... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Perinatal toxicology; Misoprostol; Malformations; Moebius syndrome; Abortion; Cytotec®. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000300005 |
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| Schüler-Faccini,Lavinia; Sanseverino,Maria Teresa Vieira; Abeche,Alberto Mantovani; Vianna,Fernanda Sales Luiz; Fraga,Lucas Rosa; Rocha,Anastacia Guimaraes; Silva,André Anjos da; Souza,Paulo Ricardo Assis de; Hilgert,Artur Hartmann; Barbosa,Camila Pocharski; Kauppinem,Caroline Grasso; Martins,Daniela Fernandes; Santos,Daniela Silva; Colpes,Gabriel Henrique; Ecco,Gabriela; Silva,Helena Margot Flores Soares da; Penteado,Louise Piva; Santos,Tatiane dos. |
| Abstract In 1990, the first Teratogen Information Service in Brazil (SIAT) was implemented in the Medical Genetics Service at Hospital de Clinicas de Porto Alegre. SIAT is a free-to-use information service both to health professionals and the general population, especially to women who are pregnant or planning pregnancy. The main objective of this paper is to present the activities of SIAT in its initial years (1990-2006), compared to those in the last decade (2007-2017). In addition we review the scientific contribution of SIAT in the field of human teratogenesis. Since 1990, SIAT received 10,533 calls. Use of medications were the main reason for concern, accounting for 74% of all questions, followed by other chemical exposures (occupational, cosmetics,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Teratogens; Pregnancy; Zika; Thalidomide; Misoprostol; Rubella. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572019000200297 |
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