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| Pigné, Sandrine; Zykwinska, Agata; Janod, Etienne; Cuenot, Stéphane; Kerkoud, Mohammed; Raulo, Roxane; Bataillé-simoneau, Nelly; Marchi, Muriel; Kwasiborski, Anthony; N’guyen, Guillaume; Mabilleau, Guillaume; Simoneau, Philippe; Guillemette, Thomas. |
| Background: Flavin-dependent monooxygenases are involved in key biological processes as they catalyze a wide variety of chemo-, regio- and enantioselective oxygenation reactions. Flavoprotein monooxygenases are frequently encountered in micro-organisms, most of which require further functional and biocatalytic assessment. Here we investigated the function of the AbMak1 gene, which encodes a group A flavin monooxygenase in the plant pathogenic fungus Alternaria brassicicola, by generating a deficient mutant and examining its phenotype. Results: Functional analysis indicates that the AbMak1 protein is involved in cell wall biogenesis and influences the melanization process. We documented a significant decrease in melanin content in the Äabmak1 strain... |
| Tipo: Text |
Palavras-chave: Monooxygenase; Cell wall; Melanin; Fungus; Flavoprotein. |
| Ano: 2017 |
URL: https://archimer.ifremer.fr/doc/00371/48189/48305.pdf |
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