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Berríos,Soledad; Manieu,Catalina; López-Fenner,Julio; Ayarza,Eliana; Page,Jesús; González,Marisel; Manterola,Marcia; Fernández-Donoso,Raúl. |
BACKGROUND: The nuclear architecture of meiotic prophase spermatocytes is based on higher-order patterns of spatial associations among chromosomal domains from different bivalents. The meiotic nuclear architecture depends on the chromosome characteristics and consequently is prone to modification by chromosomal rearrangements. In this work, we consider Mus domesticus spermatocytes with diploid chromosome number 2n = 40, all telocentric, and investigate a possible modification of the ancestral nuclear architecture due to the emergence of derived Rb chromosomes, which may be present in the homozygous or heterozygous condition. RESULTS: In the 2n = 40 spermatocyte nuclei random associations mediated by pericentromeric heterochromatin among the 19 telocentric... |
Tipo: Journal article |
Palavras-chave: Robertsonian chromosomes; Mouse spermatocytes; Bivalent associations; Nuclear architecture. |
Ano: 2014 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100016 |
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