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| Braga,Miula Portelinha; Piovesan,Augusta; Valarini,Natália; Maciel,Sandra Mara; Andrade,Flaviana Bombarda de; Poli-Frederico,Regina Célia. |
| The objective of this study was to analyze the genotypic diversity, frequency of serotypes and the detection of mutacins from Streptococcus mutans isolates in caries-free and caries-active individuals.A total of 260 S. mutans isolated from 28 individuals with and without dental caries were subjected to AP-PCR and PCR screening of glucosyltransferase B, mutacin and serotype genes, which showed the presence of. 70 different genotypes. There was no statistically significant association between the presence of genes for serotypes and mutacins with dental caries. However, there was a statistically significant and a strong association between the higher genotypic diversity in the subjects with caries (r = 0.72, p = 0.001). There was an increase in the number of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Dental caries; Genotypic diversity; Mutacin; Serotype; Streptococcus mutans. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132013000200009 |
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| Kamiya,Regianne Umeko; Taiete,Tiago; Gonçalves,Reginaldo Bruno. |
| The colonization and accumulation of Streptococcus mutans are influenced by various factors in the oral cavity, such as nutrition and hygiene conditions of the host, salivary components, cleaning power and salivary flow and characteristics related with microbial virulence factors. Among these virulence factors, the ability to synthesize glucan of adhesion, glucan-binding proteins, lactic acid and bacteriocins could modify the infection process and pathogenesis of this species in the dental biofilm. This review will describe the role of mutacins in transmission, colonization, and/or establishment of S. mutans, the major etiological agent of human dental caries. In addition, we will describe the method for detecting the production of these inhibitory... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Streptococcus mutans; Mutacin; Mutacintyping. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822011000400001 |
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