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The CK1 gene family: expression patterning in zebrafish development Biol. Res.
ALBORNOZ,AMELINA; YÁÑEZ,JOSÉ M; FOERSTER,CLAUDIA; AGUIRRE,CELESTE; PEREIRO,LUISA; BURZIO,VERÓNICA; MORAGA,MAURICIO; REYES,ARIEL E; ANTONELLI,MARCELO.
Protein kinase CK1 is a ser/thr protein kinase family which has been identified in the cytosol cell fraction, associated with membranes as well as in the nucleus. Several isoforms of this gene family have been described in various organisms: CK1á, CK1ß, CK1δ, CK1å and CK1γ. Over the last decade, several members of this family have been involved in development processes related to wnt and sonic hedgehog signalling pathways. However, there is no detailed temporal information on the CK1 family in embryonic stages, even though orthologous genes have been described in several different vertebrate species. In this study, we describe for the first time the cloning and detailed expression pattern of five CK1 zebrafish genes. Sequence analysis...
Tipo: Journal article Palavras-chave: CK1; Casein Kinase 1; Expression pattern; Development; Zebrafish; Otic vesicles; Retina; Lens; Pectoral fin bud; Tegmentum; Myelencephalon; Telencephalon; Diencephalon; Mesencephalon; Rhombomeres.
Ano: 2007 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602007000200015
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