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Bone marrow cytological evaluation in dogs with chronic kidney disease Arq. Bras. Med. Vet. Zootec.
Borin-Crivellenti,S.; Crivellenti,L.Z.; Carvalho,M.B.; Santana,A.E..
Since anemia is indicated as an important compromising factor for the quality of life of dogs with chronic kidney disease (CKD), bone marrow cytological analysis may provide more information on the hematological profile these dogs and, therefore, allow clinicians to not only choose the most adequate treatment but also monitor the response to therapy. The aim of this study was to investigate the feasibility with sternal bone marrow puncture in chronic kidney disease (CKD) using only local anesthesia and check if the cytological analysis is helpful to determine the hematological status. We found that erythroid hypoplasia occurred only in terminal CKD patients, and that the bone marrows of dogs with CKD stages 2 and 3 were quantitatively similar to those of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Dog; Anemia; Myelogram; Erythropoiesis; Renal failure.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352014000601751
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Aqueous wheat extract (Triticuma estivum) prevents carboplatin-induced myelosuppression and oxidative stress in Wistar rats Ciência Rural
Forlani,Gustavo Soares; Félix,Samuel Rodrigues; Teixeira,Luciele Varaschini; Michelon,Laura; Bastos,Rodrigo Franco; Ribeiro,Carmen Lúcia Garcez; Freitag,Rogério Antônio; Félix,Anelize de Oliveira Campello; Nobre,Márcia de Oliveira.
ABSTRACT: The present study aimed to evaluate the use of aqueous wheat extracts as an adjunct to antineoplastic therapy with carboplatin. In this study, 32 rats were used which were randomly distributed into 4 groups: G1 - negative control; G2 - control treated with physiological solution; G3 - animals treated with aqueous extract of wheat in the concentration of 100mg/kg; G4 - animals treated with aqueous wheat extract at the concentration of 400mg/kg; 300mg/m² of carboplatin was administered intraperitoneally at day 0 in animals from groups G2, G3, and G4, whereas 1ml of physiological solution was administered by the same route in animals from group G1. Animals were treated daily for 21 days by orogastric gavage according to their respective...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Chemotherapy; Phytochemical; Paraoxanase1; Myelogram.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782018001000600
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