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MURTHY,K. R. KRISHNA. |
Death caused by scorpion envenoming (Buthidae family) is a common event in tropical and subtropical countries. Severe scorpion envenoming causes an autonomic storm resulting in a massive release of catecholamines, angiotensin II, glucagon, cortisol, and changes in insulin secretion. As a consequence of these changes in the hormonal milieu, scorpion envenoming results in a syndrome of fuel energy deficits and an inability of the vital organs to utilize the existing metabolic substrates, which causes myocardial damage, cardiovascular disturbances, peripheral circulatory failure, pulmonary oedema, and many other clinical manifestations alone or in combination, producing multi-system-organ-failure (MSOF) and death. Insulin-glucose infusion or antivenom... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Catecholamines; Angiotensin II; Glucagon; Cortisol; Insulin; Myocardial damage; Cardiovascular disturbances; Peripheral circulatory failure; Pulmonary oedema; Multi-system-organ-failure (MSOF). |
Ano: 2000 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79302000000100002 |
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YUGANDHAR,B.; RADHA KRISHNA MURTHY,K.; SATTAR,S. A.. |
The efficacy of insulin-glucose infusion in reversing myocardial damage, haemodynamic changes, peripheral circulatory failure, and pulmonary oedema was evaluated in 25 victims of venomous scorpion stings from the Rayalaseema region in the south of India. Myocardial damage with peripheral circulatory failure was seen in all scorpion sting victims. Ten of these victims also had pulmonary oedema. All the patients received continuous infusion of regular crystalline insulin at the rate of 0.3 U/g of glucose and glucose at the rate of 0.1 g/kg/h with supplementary potassium as needed, inotropic agents, oxygen, as well as maintenance of fluid, electrolytes and acid-base balance. Insulin-glucose infusion was associated with reversal of cardiovascular and... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Scorpion; Myocardial damage; Pulmonary oedema; Insulin-glucose infusion; Peripheral circulatory failure. |
Ano: 1999 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79301999000200007 |
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