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	Provedor de dados International Journal of Morphology (2) BJMBR (1) Autor Al Humayed,Suliman (1) Al-Ani,Bahjat (1) Almasi,Fatemeh (1) Eid,Refaat A (1) Ghanbari,Ali (1) Haidara,Mohamed A (1) Han,Chao (1) Khazaei,Mozafar (1) Li,Jingyi (1) Li,Shan (1) Liu,Xiaogang (1) Ma,Yuanyuan (1) Shatoor,Abdullah S (1) Wang,Xiaoman (1) Zaki,Mohamed Samir A (1) Zhang,Jielei (1) Zhang,Lixia (1) Zheng,Lili (1) chehrei,Shima (1) Mais... Palavra-chave NAFLD (3) Hepatic steatosis (2) Cholesterol (1) Crataegus aronia (1) FTO (1) GLP-1 (1) Mitochondrial dysfunction (1) PI3K (1) Rat (1) Simvastatin (1) Tribulus Terrestris (1) Mais... Tipo do documento Journal article (2) Info:eu-repo/semantics/article (1) Ano 2018 (1) 2017 (2) País Chile (2) Brazil (1) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Hepatoprotective Effects of Tribulus terrestris Hydro-Alcholic Extract on Non-Alcoholic Fatty Liver- Induced Rats International Journal of Morphology Almasi,Fatemeh; Khazaei,Mozafar; chehrei,Shima; Ghanbari,Ali. Non-alcoholic fatty liver induces many complications to the liver tissue and also serum related parameters. Medicinal plants are the safe therapeutic strategy for the treatment of diseases. In this regards, the present study was conducted to evaluate the effect of Tribulus terrestris (T. terrestris) extract on non-alcoholic fatty liver in rats. In this experimental study, thirty male Wistar rats were divided into five groups (n=6). Animals in experimental groups were received high fructose diet (70 %) (HDF) daily alone or in combined with daily intraperitoneal injection of 500, 700 and 1000 mg/kg extract of T. terrestris. Control group of rats was feed with standard chow. The serum levels of biomarkers of liver and serum lipid profiles were assessed, also... Tipo: Journal article Palavras-chave: Cholesterol; NAFLD; Rat; Tribulus Terrestris. Ano: 2017 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022017000100054 Differential Therapeutic Effects of Crataegus aronia and Simvastatin on the Hepatocyte Ultrastructure in Hepatic Steatosis International Journal of Morphology Al Humayed,Suliman; Eid,Refaat A; Shatoor,Abdullah S; Haidara,Mohamed A; Zaki,Mohamed Samir A; Al-Ani,Bahjat. Complications of fat accumulation in liver, hepatic steatosis such as liver cirrhosis and liver failure are among the common public health problems. We sought to investigate the damage to the hepatocyte ultrastructure induced by high fat diets (HFD) and compared the therapeutic effects at the cellular level of two antioxidant and lipid lowering agents; Crataegus aronia extracts and simvastatin on hepatic steatosis. Rats were either fed with HFD (model group) or low fat diets (LFD) (control group) for 15 weeks before being sacrificed and therapeutic groups started the treatment with these agents after week 11 until the sacrifice day. Harvested liver tissues were examined using transmission electron microscopy (TEM) and liver homogenates were assayed for... Tipo: Journal article Palavras-chave: Hepatic steatosis; Mitochondrial dysfunction; NAFLD; Crataegus aronia; Simvastatin. Ano: 2017 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022017000200032 Exenatide ameliorates hepatic steatosis and attenuates fat mass and FTO gene expression through PI3K signaling pathway in nonalcoholic fatty liver disease BJMBR Li,Shan; Wang,Xiaoman; Zhang,Jielei; Li,Jingyi; Liu,Xiaogang; Ma,Yuanyuan; Han,Chao; Zhang,Lixia; Zheng,Lili. Non-alcoholic fatty liver disease (NAFLD) is a common disease associated with metabolic syndrome and can lead to life-threatening complications like hepatic carcinoma and cirrhosis. Exenatide, a glucagon-like peptide-1 (GLP-1) receptor agonist antidiabetic drug, has the capacity to overcome insulin resistance and attenuate hepatic steatosis but the specific underlying mechanism is unclear. This study was designed to investigate the underlying molecular mechanisms of exenatide therapy on NAFLD. We used in vivo and in vitro techniques to investigate the protective effects of exenatide on fatty liver via fat mass and obesity associated gene (FTO) in a high-fat (HF) diet-induced NAFLD animal model and related cell culture model. Exenatide significantly... Tipo: Info:eu-repo/semantics/article Palavras-chave: GLP-1; FTO; NAFLD; PI3K; Hepatic steatosis. Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000800612 Registros recuperados: 3 Primeira ... 1 ... Última

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