|
|
|
| Registros recuperados: 33 | |
|
|
| shaker, ahmed mahmoud. |
| The Egyptian cotton leaf worm, Spodoptera littoralis (Boisd.) (Noctuidae: Lepidoptera) is an economically important pest with a wide range of host plants. It attacks certain vegetable and field crops such as cotton, tomatoes, cabbage and squash in Egypt, for causing severe injuries to the plants in all phonological crop stages, In addition to this species has acquired resistance to many insecticides. The overall objective of this investigations was to look for new control strategy through evaluate the effects of application of TiO2 nanoparticles on the survival and biology of this insect. The experiment were carried out under laboratory conditions, the experiment was achieved with two treatments, consisting of TiO2 nanoparticles application, and a negative... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: TiO2; Nanoparticles; Cotton; Leaf worm; Nanopesticide; Agriculture. |
| Ano: 2018 |
URL: http://www.cigrjournal.org/index.php/Ejounral/article/view/4390 |
| |
|
|
| CASTRO,RICARDO I.; FORERO-DORIA,OSCAR; GUZMÁN,LUIS. |
| Abstract Currently, cancer is the second most common cause of death in the United States, exceeded only by heart disease. Chemotherapy traditionally suffers from a non-specific distribution, with only a small fraction of the drug reaching the tumor, in this sense, the use of dendrimers incorporating drugs non-covalently encapsulated inside the dendrimer or covalently conjugated have proven to be effectives against different cancer cell lines. However, at present the dendrimers used as drug-carriers still do not meet the necessary characteristic to be considered as an ideal dendrimer for drug delivery; high toxicity, bio-degradability, low toxicity, biodistribution characteristics, and favorable retention with appropriate specificity and bioavailability... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Dendrimers; Cancer therapy; Pharmacodynamics; Nanoparticles. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000502331 |
| |
|
|
| VARANDA,LAUDEMIR C.; SOUZA,CAIO G.S.; MORAES,DANIEL A.; NEVES,HERBERT R.; SOUZA JUNIOR,JOÃO B.; SILVA,MONICA F.; BINI,RAFAEL A.; ALBERS,REBECCA F.; SILVA,TIAGO L.; BECK JUNIOR,WATSON. |
| Abstract: Since its inception in 2007, the Colloidal Materials Group, one of the research groups in nanotechnology of the Institute of Chemistry of São Carlos (IQSC) at University of São Paulo (USP) carries out studies related to the development of syntheses methods of nanoparticles and multifunctional nanostructured systems. Our works search new synthesis methodologies that allow high size and shape control of the individual nanoparticles or that compose the nanostructured systems and has as a principle the synthetic approaches based on the modified polyol and thermal decomposition processes. Systems involving nanoparticles have received extensive attention both in the fundamental research and in several technological applications exploring the unique... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Nanoparticles; Nanostructured composites; Modified polyol process; Thermal decomposition method; Size and shape control; Colloidal Materials Group.. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000700406 |
| |
|
|
| RIBEIRO,ANA F.; SANTOS,JULIANA F.; MATTOS,RÔMULO R.; BARROS,ELIANE G.O.; NASCIUTTI,LUIZ EURICO; CABRAL,LÚCIO M.; SOUSA,VALERIA P. DE. |
| Abstract Uncaria tomentosa (UT) extracts have been shown to have promising anti-tumor activity. We hypothesized that its incorporation into nanostructured systems could improve the anticancer properties. Here, poly-e-caprolactone (PCL) and poly-d,l-lactide-co-glycolide (PLGA) were employed to generate nanoparticles loaded with UT extract in a single emulsion solvent evaporation method. The nanoparticles were characterized by particle size, zeta potential, morphology and entrapment efficiency along with stability and release profiles. The nanoparticles presented entrapment efficiencies above 60% and a mean diameter below 300nm. UT-PCL nanoparticles presented higher entrapment efficiency and mean particle size as well as a slow release rate. The UT-PLGA... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Nanoparticles; Prostate cancer; PLGA; PCL; Anti-tumor; Anti-cancer; Cat’s Claw. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652020000100908 |
| |
|
|
| IANISKI,FRANCINE R.; RECH,VIRGINIA C.; NISHIHIRA,VIVIAN S.K.; ALVES,CATIANE B.; BALDISSERA,MATHEUS D.; WILHELM,ETHEL A.; LUCHESE,CRISTIANE. |
| ABSTRACT Considering that Alzheimer's disease is a prevalent neurodegenerative disease worldwide, we investigated the activities of three key kinases: creatine kinase, pyruvate kinase and adenylate kinase in the hippocampus and cerebral cortex in Alzheimer's disease model. Male adult Swiss mice received amyloid-β or saline. One day after, mice were treated with blank nanocapsules (17 ml/kg) or meloxicam-loaded nanocapsules (5 mg/kg) or free meloxicam (5 mg/kg). Treatments were performed on alternating days, until the end of the experimental protocol. In the fourteenth day, kinases activities were performed. Amyloid-β did not change the kinases activity in the hippocampus and cerebral cortex of mice. However, free meloxicam decrease the creatine kinase... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Alzheimer's disease; Nanoparticles; Meloxicam; Energetic metabolism; Phosphoryltransfer network. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016000501829 |
| |
|
|
| Rivas-Aravena,Andrea; Sandino,Ana María; Spencer,Eugenio. |
| Aquaculture has become an important economic sector worldwide, but is faced with an ongoing threat from infectious diseases. Vaccination plays a critical role in protecting commercially raised fish from bacterial, viral and parasitic diseases. However, the production of effective vaccines is limited by the scarcity of knowledge about the immune system of fish. Improving vaccines implies using antigens, adjuvants and employing methods of administration that are more effective and less harmful to the fish. In this context, in recent year there have studies of methods of encapsulating antigens in matrices of different types to apply in fish vaccines. This work reviews the new methods to improve fish vaccines by encapsulating them in polymers and... |
| Tipo: Journal article |
Palavras-chave: Nanoparticles; Vaccine; Aquaculture. |
| Ano: 2013 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602013000400012 |
| |
|
| |
|
|
| Margabandhu,M.; Sendhilnathan,S.; Senthilkumar,S.; Gajalakshmi,D.. |
| ABSTRACT In the present work, Cu2+ substituted cobalt ferrite (Co1-xCuxFe2O4, x = 0, 0.3, 0.5, 0.7 and 1) magnetic nanopowders were synthesized via chemical co-precipitation method. The prepared powders were investigated by various characterization methods such as X-ray diffraction analysis (XRD), scanning electron microscope analysis (SEM), vibrating sample magnetometer analysis (VSM) and fourier transform infrared spectroscopy analysis (FTIR). The XRD analysis reveals that the synthesized nanopowders possess single phase centred cubic spinel structure. The average crystallite size of the particles ranging from 27-49 nm was calculated by using Debye-scherrer formula. Magnetic properties of the synthesized magnetic nanoparticles are studied by using VSM.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Nanoparticles; Co-precipitation; Cubic spinel; Morphology; Anti-bacterial activity. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132016000300401 |
| |
|
| |
|
|
| Guan,Jiao; Han,Liqin; Shi,Nianqiu; Zhu,Heyun; Wang,Junmin. |
| Docetaxel-loaded acetic acid conjugated Cordyceps sinensis polysaccharide (DTX-AA-CSP) nanoparticles were prepared through dialysis and their release rates in vitro, particle sizes, zeta potentials, drug loading capacities, and encapsulation efficiencies were characterized for the synthesis of AA-modified CSPs from traditional Chinese medicine Cordyceps sinensis (Berk.) Sacc. Then, the AA-modified CSPs were characterized by 1H-NMR and FT-IR. Furthermore, the biocompatibility of the delivery carrier (AA-CSP nanoparticles) was assessed on human umbilical vein endothelial cells. In vitro antitumor activity studies on DTX-AA-CSP nanoparticles were conducted on the human liver (HepG2) and colon cancer cells (SW480). The DTX-AA-CSP nanoparticles were spherical... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Docetaxel; Cordyceps sinensis polysaccharide; Nanoparticles; Antitumor efficacy; Biocompatibility. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100599 |
| |
|
|
| Roy,René; Shiao,Tze Chieh; Rittenhouse-Olson,Kate. |
| Combining nanotechnology with glycobiology has triggered an exponential growth of research activities in the design of novel functional bionanomaterials (glyconanotechnology). More specifically, recent synthetic advances towards the tailored and versatile design of glycosylated nanoparticles namely glyconanoparticles, considered as synthetic mimetics of natural glycoconjugates, paved the way toward diverse biomedical applications. The accessibility of a wide variety of these structured nanosystems, in terms of shapes, sizes, and organized around stable nanoparticles have readily contributed to their development and applications in nanomedicine. In this context, glycosylated gold-nanoparticles (GNPs), glycosylated quantum dots (QDs), fullerenes, single-wall... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Dendrimer; Glycodendrimer; Vaccine; Bacteria; Nanoparticles; E. coli; Lanthanides. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502013000700008 |
| |
|
|
| Rodrigues,Caroline Danziato; Khalil,Najeh Maissar; Mainardes,Rubiana Mara. |
| In this work, we developed and validated an effective reversed-phase HPLC method with photodiode array (PDA) detection for the quantitative analysis of amphotericin B (AmB) in poly(lactide)-poly(ethylene glycol) (PLA-PEG) blend nanoparticles. Chromatographic runs were performed on a reverse phase C18 column using a mobile phase comprising a 9% acetic acid and acetonitrile mixture (40:60, v/v) under isocratic elution with a flow rate of 1 mL/min. AmB was detected at a wavelength of 408 nm. The validation process was performed considering the selectivity, linearity, precision, accuracy, robustness, limit of detection (LOD) and limit of quantitation (LOQ) of the method. A concentration range of 1-20 µg/mL was used to construct a linear calibration curve. The... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Amphotericin B/determination; Amphotericin B/encapsulation; High performance liquid chromatography/reverse phase/quantitative analysis; Nanoparticles. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502014000400859 |
| |
|
| |
|
|
| Vijayaraj,Surendran; Palei,Narahari N; Archana,Devalapalli; Lathasri,Kuppam; Rajavel,Ponnusamy. |
| Rutin is a flavonoid glycoside, mainly consists of phenolic compounds, responsible for many biological activities. The objective of the present study was to develop and validate a precise, simple, robust, rapid and reliable reverse phase high -performance liquid chromatography (RP-HPLC) technique by using Qbd approach for evaluating the rutin in nanoparticles. Central composite design (CCD) was employed for optimizing the experimental conditions of RP-HPLC method. Buffer pH, methanol content in the mobile phase composition, flow rate, and wavelength were selected as independent variables whereas retention time, peak area, and asymmetry factor was selected as dependent variables. The retention time, peak area and asymmetric factor of rutin by using... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Rutin; Chitosan; Sodium aliginate; Nanoparticles; RP-HPLC; Central composite design; QbD. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100632 |
| |
|
|
| Pedrozo,Regiellen Cristina; Antônio,Emilli; Khalil,Najeh Maissar; Mainardes,Rubiana Mara. |
| Rutin is a flavonoid compound obtained from different vegetables and fruits; specifically, it is found in the seeds of buckwheat and in fruit peels, particularly citrus. It is also an important constituent of red wine. Rutin exhibits various biological properties including antiviral, vasoprotective, anti-inflammatory, and anticarcinogenic activities. However, its antioxidant activity is the most well studied. Despite the potential for in vitro applications, rutin presents low oral bioavailability that affects its biological activities. Nanoparticles composed of polymers, protein, or lipids are of great importance in the pharmaceutical and nutraceutical areas due to their physicochemical properties, which improve the pharmacokinetics of the drug which is... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Nano spray drying; Rutin; Nanoparticles; Bovine serum albumin; Antioxidant. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100512 |
| |
|
| |
|
| |
|
| |
|
|
| Gatti,Tiago Henrique Honorato; Eloy,Josimar Oliveira; Ferreira,Leonardo Miziara Barboza; Silva,Isabel Cristine da; Pavan,Fernando Rogério; Gremião,Maria Palmira Daflon; Chorilli,Marlus. |
| Abstract Mucoadhesive nanoparticles are particularly interesting for delivery through nasal or pulmonary routes, as an approach to overcome the mucociliary clearance. Moreover, these nanoparticles are attractive for peptide and protein delivery, particularly for insulin to treat diabetes, as an alternative to conventional parenteral administration. Thus, chitosan, a cationic mucoadhesive polysaccharide found in shells of crustaceans, and the negatively-charged dextran sulfate are able to form nanoparticles through ionic condensation, representing a potential insulin carrier. Herein, chitosan/dextran sulfate nanoparticles at various ratios were prepared for insulin loading. Formulations were characterized for particle size, zeta potential, encapsulation... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Insulin; Chitosan; Dextran-Sulfate; Nanoparticles; Mucoadhesion.. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000100623 |
| |
|
|
| Ianiski,Francine Rodrigues; Laporta,Luciane Varini; Rubim,Alexandre Machado; Luchese,Cristiane. |
| abstract A method to ensure that an analytical method will produce reliable and interpretable information about the sample must first be validated, making sure that the results can be trusted and traced. In this study, we propose to validate an analytical high performance liquid chromatography (HPLC) method for the quantitation of meloxicam loaded PEGylated nanocapsules(M-PEGNC). We performed a validation study, evaluated parameters including specificity, linearity, quantification limit, detection limit, accuracy, precision and robustness. PEGylated nanocapsules were prepared by interfacial deposition of preformed polymer, and the particle size, polydispersity index, zeta potential, pH value and encapsulation efficiency were characterized. The proposed... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: High performance liquid chromatography/quantitative analysis; Meloxicam/determination; PEGylated nanocapsules/quality control; Nanoparticles; Poly(ethylene glycol).. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000400823 |
| |
| Registros recuperados: 33 | |
|
|
|
