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	Provedor de dados Biol. Res. (1) BJMBR (1) Genet. Mol. Biol. (1) Autor Duan,X-Y. (1) Fu,Lei (1) Guo,Y-M. (1) JIAN,HU (1) LI,SUN (1) LU-MING,WANG (1) Li,M. (1) Li,Y. (1) SU-JUN,JIANG (1) Shang,Xiaopu (1) Wang,Rong (1) Wang,W. (1) Yin,Ling (1) Zhang,Pengjun (1) Zhang,Runtong (1) Mais... Palavra-chave Non-small cell lung cancer (3) 18F-FDG PET/CT (1) ABCG2 (1) Chemotherapy (1) DNA sequencing (1) Meta-analysis (1) Nuclear of export signal (1) Nuclear of localization signal (1) Polymorphism (1) Prediction (1) Standardized uptake value (SUV) (1) Telomeric repeat binding factor 1 (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Journal article (1) Ano 2019 (1) 2015 (1) 2009 (1) País Brazil (2) Chile (1) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Analysis of the nuclear localization signal of TRF1 in non-small cell lung cancer Biol. Res. JIAN,HU; LI,SUN; LU-MING,WANG; SU-JUN,JIANG. Several studies revealed a similar down-regulation of telomeric repeat binding factor 1 (TRF1) in tumors. We have previously reported the TRFl expression levels were down-regulation in non-small cell lung cancer (NSCLC). The regulation of TRFl localization is proposed to be important for the function and expression. The nuclear localization signal (NLS) and nuclear export signal (NES) are often important clues to localization of protein. The objective of the present study was to investigate the NLS and NES of TRFl in NSCLC patients. Thirty (30) patients with NSCLCs had undergone radical operations in The First Affiliated Hospital, College of Medicine, Zhejiang University. DNA sequences of NLSs and NESs were amplified by PCR. The PCR products were analyzed... Tipo: Journal article Palavras-chave: Non-small cell lung cancer; Telomeric repeat binding factor 1; Nuclear of localization signal; Nuclear of export signal; DNA sequencing. Ano: 2009 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602009000200010 Predictive significance of standardized uptake value parameters of FDG-PET in patients with non-small cell lung carcinoma BJMBR Duan,X-Y.; Wang,W.; Li,M.; Li,Y.; Guo,Y-M.. 18F-fluoro-2-deoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) is widely used to diagnose and stage non-small cell lung cancer (NSCLC). The aim of this retrospective study was to evaluate the predictive ability of different FDG standardized uptake values (SUVs) in 74 patients with newly diagnosed NSCLC. 18F-FDG PET/CT scans were performed and different SUV parameters (SUVmax, SUVavg, SUVT/L, and SUVT/A) obtained, and their relationship with clinical characteristics were investigated. Meanwhile, correlation and multiple stepwise regression analyses were performed to determine the primary predictor of SUVs for NSCLC. Age, gender, and tumor size significantly affected SUV parameters. The mean SUVs of squamous cell carcinoma were... Tipo: Info:eu-repo/semantics/article Palavras-chave: 18F-FDG PET/CT; Standardized uptake value (SUV); Prediction; Non-small cell lung cancer. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015000300267 A meta-analysis of ABCG2 gene polymorphism and non-small cell lung cancer outcomes Genet. Mol. Biol. Fu,Lei; Wang,Rong; Yin,Ling; Shang,Xiaopu; Zhang,Runtong; Zhang,Pengjun. Abstract We aimed to analyze the correlation between ABCG2 gene polymorphisms of 34 GG/(GA + AA) loci, 421 CC/(AC + AA) loci, and non-small cell lung cancer (NSCLC) therapeutic effects via meta-analysis. With key words, the databases PubMed and EMBASE were searched for clinical studies on ABCG2 polymorphism and NSCLC. RR and 95% CIs were used to compute combined effects, followed by heterogeneity testing. Publication bias was examined using the funnel plot method. Review Manager 5.3 software was used for the meta-analysis. Ten studies were included. No evidence of heterogeneity exists in these studies. The results indicate that two polymorphic loci of ABCG2 gene (34 G>A, and 421 C>A) had no relationship with the curative effect of chemotherapy for... Tipo: Info:eu-repo/semantics/article Palavras-chave: ABCG2; Polymorphism; Non-small cell lung cancer; Chemotherapy; Meta-analysis. Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572019000500105 Registros recuperados: 3 Primeira ... 1 ... Última

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