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	Provedor de dados BJPS (1) Autor Chierentin,Lucas (1) Salgado,Hérida Regina Nunes (1) Palavra-chave Antimicrobials/quality control (1) Microbiological assay (1) Norfloxacin/quantification in tablets (1) Quality control (1) Turbidimetric method/quality control/validation (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2015 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Development and validation of a rapid turbidimetric assay to determine the potency of norfloxacin in tablets BJPS Chierentin,Lucas; Salgado,Hérida Regina Nunes. Norfloxacin is one of the first commercially available (and most widely used) fluoroquinolone antibiotics. This paper reports the development and validation of a simple, sensitive, accurate and reproducible turbidimetric assay method to quantify norfloxacin in tablets formulations in only 4 hours. The bioassay is based on the inhibitory effect of norfloxacin upon the strain ofStaphylococcus epidermidis ATCC 12228 IAL 2150 used as test microorganism. The assay was performed 3x3 parallel lines like, three tubes for each concentration of reference substance and three tubes for each sample concentration. The results were treated statistically by analysis of variance and were found to be linear (r2 = 0.9999) in the selected range of 25-100 μg mL-1; precise... Tipo: Info:eu-repo/semantics/article Palavras-chave: Microbiological assay; Quality control; Norfloxacin/quantification in tablets; Turbidimetric method/quality control/validation; Antimicrobials/quality control. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000300629 Registros recuperados: 1 Primeira ... 1 ... Última

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