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Biodistribution of 99Mo in rats BABT
Souza,Raphael Sancho Sisley de; Ribeiro,Bianca da Silva; Dantas,Ana Letícia Almeida; Bernardo Filho,Mario; Dantas,Bernardo Maranhão.
The modification of 99Mo standard metabolism in the presence of MDP would alter the dosimetry of this radionuclide in nuclear medicine patients. Therefore, the objective of this work is to evaluate the influence of MDP in the biodistribution of 99Mo. Wistar rats were divided in two groups of six animals, being inoculated respectively 99Molibdate and 99Mo+MDP via plex ocular. The biodistribution study was carried out after 10 and 120 minutes respectively. The organs were counted with a NaI(Tl) detector. The uptake values did not present significant differences among the groups. An in vitro study through planar chromatography was carried out to determine the affinity between molybdenum and MDP. The results show that 99Mo has low affinity both to propanone...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Wistar; Molybdenum; Nuclear Medicine.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000700029
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Importance of the nutritional status for the interpretation of nuclear medicine examinations BABT
Moura,Egberto Gaspar de; Passos,Magna Cottini Fonseca.
Malnutrition is very prevalent in the Third World, but still in developing Countries and is found in certain communities in developed Countries. Several laboratories examinations are affected by malnutrition. Recently, gestational or neonatal malnutrition were considered to contribute to the development of chronic diseases in adulthood, this phenomena was named programming or metabolic imprinting. Similar consideration were suggested for Nuclear Medicine examinations. Here we review the literature about this aspect and present our own data showing changes in biodistribution of a radiopharmaceutical compound in different animal models of adult malnutrition or caused by maternal malnutrition programming.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Programming; Nuclear Medicine; Malnutrition; Biodistribution; Radiopharmaceuticals.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132002000500021
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