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| Borkosky,Silvia S.; Nagatsuka,Hitoshi; Orita,Yorihisa; Tsujigiwa,Hidetsugu; Yoshinobu,Junko; Gunduz,Mehmet; Rodriguez,Andrea P.; Missana,Liliana R.; Nishizaki,Kazunori; Nagai,Noriyuki. |
| The Notch signaling pathway is an evolutionary conserved mechanism that plays an important role in cell-cell communication and cell fate in a wide range of tissues. The mammalian family of Notch receptors consists of 4 members: Notch1/2/3/4. The Notch ligand family consists of 5 members: Delta1/3/4 and Jagged1/2. Math1 encodes a murine basic helix-loop-helix (bHLH) transcription factor that acts as positive regulator of cell differentiation. Recently, links between Notch and Math1 pathways were demonstrated in various tissues. Expression of Notch1, Jagged2 and Math1 were analyzed in the mouse molar tooth germ during embryonic stage (E) 13 and E15 and during postnatal stage (PN) 1, PN3, PN5, PN10 and PN14 by using in situ hybridization. Positive Notch1... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Notch signaling; Odontogenesis; Cell differentiation; Molar morphogenesis. |
| Ano: 2008 |
URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0327-95452008000300006 |
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| Borie E,Eduardo; Oporto V,Gonzalo; Aracena R,Daniel. |
| Tooth development occurs through the interaction between oral tissues during embryogenesis. Alteration through odontogenesis may cause tooth morphological alterations, one of these could be Dens evaginatus. This anatomical variation could be originated from an abnormal proliferation and folding of a portion of the inner enamel epithelium and subjacent ectomesenchymal cells of the dental papilla into the stellate reticulum of the enamel organ during the bell stage of tooth formation. Dens evaginatus is defined as a tubercle, or supplemental solid elevation on some portion of the crown surface. Inadequate clinical management of these teeth may result in a pulpal exposure and possible loss of vitality of the tooth. The research wants to report a case of Dens... |
| Tipo: Journal article |
Palavras-chave: Dental morphology; Dens evaginatus; Odontogenesis; Hemophilia. |
| Ano: 2010 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022010000200006 |
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| Iglesias,Déborah Pitta Paraíso; Rego,Moacyr Jesus Barreto de Melo; Beltrão,Eduardo Isidoro Carneiro; Sobral,Ana Paula Veras. |
| Many of Glycobyological aspects of human development remain still unclear, mainly in oral science, and this could be observed in a lack of literature with few and old papers about this subject. During tooth histo-morphogenesis changes occur in basement membrane composition, expression of signaling molecules and in localization of cell surface components, where glyco components could be involved. In this sense, this work aimed to analyze the ConA ligands commonly founded in glycoproteins cores and UEA-I ligands since fucolization is a Key event in many physiological and pathological processes. Therefore 15 jaws of human fetuses were ethically obtained, histologicaly processed and then submitted to lectin histochemistry with appropriated controls. The... |
| Tipo: Journal article |
Palavras-chave: Odontogenesis; Carbohydrates; Lectin histochemistry. |
| Ano: 2012 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000300056 |
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