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	Provedor de dados BJPS (3) BJMBR (1) Autor Ali,Gowhar (2) Shah,Rehmat (2) Subhan,Fazal (2) Ullah,Ihsan (2) Ullah,Sami (2) Ahmad,Hussain (1) Hanna,M.M. (1) Haq,Matiul (1) Khan,Qasim Riaz (1) Krishnamoorthy,Venkateskumar (1) Moreno,R.A. (1) Prasad,Verma Priya Ranjan (1) Suchandrasen, (1) Sultan,Sayed Mohammad (1) Sultan,Syed Muhammad (1) Tavares,S.M. (1) Wang,Y .P. (1) Mais... Palavra-chave Olanzapine (4) Risperidone (2) Antipsychotic drugs/evaluation (1) Antipsychotics (1) Bipolar disorder (1) Haloperidol (1) Histopathology/pancreas (1) Insulin (1) Mania (1) Mannitol (1) Pancreas (1) Polysomnographic measurements (1) Quetiapine (1) Sleep (1) Solid dispersions (1) Mais... Tipo do documento Info:eu-repo/semantics/article (4) Ano 2019 (1) 2018 (1) 2012 (1) 2007 (1) País Brazil (4) Idioma Inglês (4)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 4 Primeira ... 1 ... Última A double-blind comparison of the effect of the antipsychotics haloperidol and olanzapine on sleep in mania BJMBR Moreno,R.A.; Hanna,M.M.; Tavares,S.M.; Wang,Y .P.. The effects of haloperidol and olanzapine on polysomnographic measures made in bipolar patients during manic episodes were compared. Twelve DSM-IV mania patients were randomly assigned to receive either haloperidol (mean ± SD final dosage: 5.8 ± 3.8 mg) or olanzapine (mean ± SD final dosage: 13.6 ± 6.9 mg) in a 6-week, double-blind, randomized, controlled clinical trial. One-night polysomnographic evaluation was performed before and after the haloperidol or olanzapine treatment. Psychopathology and illness severity were rated respectively with the Young Mania Rating Scale (YMRS) and the Clinical Global Impressions - Bipolar version (CGI-BP). There was a significant improvement in the YMRS and CGI-BP scores at the end of the study for both groups. Mixed... Tipo: Info:eu-repo/semantics/article Palavras-chave: Olanzapine; Haloperidol; Sleep; Mania; Bipolar disorder; Polysomnographic measurements. Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000300011 Metabolic dysregulation in early onset psychiatric disorder before and after exposure to antipsychotic drugs BJPS Shah,Rehmat; Subhan,Fazal; Sultan,Syed Muhammad; Haq,Matiul; Ahmad,Hussain; Khan,Qasim Riaz; Ali,Gowhar; Ullah,Sami; Ullah,Ihsan. Antipsychotic Drugs (APDs) are being widely prescribed to treat various disorders, including schizophrenia and bipolar disorder; however, abnormal glucose metabolism and weight gain have been reported with Atypical Anti-Psychotic drugs (AAPDs) that can lead to insulin-resistance and type 2 diabetes mellitus. The study was designed to assess various biochemical parameters including insulin and blood sugar before and after exposure to APDs in order to exclude the involvement of psychiatric disorders and certain other factors in metabolic dysregulations. Fifty seven APDs-naïve patients with first episode psychosis were divided into six groups who received olanzapine, quetiapine, risperidone, aripiprazole, haloperidol or combination of olanzapine with... Tipo: Info:eu-repo/semantics/article Palavras-chave: Olanzapine; Quetiapine; Risperidone; Antipsychotics; Pancreas; Insulin. Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100535 Physicochemical characterization and in vitro dissolution behavior of olanzapine-mannitol solid dispersions BJPS Krishnamoorthy,Venkateskumar; Suchandrasen,; Prasad,Verma Priya Ranjan. The objective of the present work is to study the dissolution behavior of olanzapine from its solid dispersions with mannitol. Solid dispersions were prepared by melt dispersion method and characterized by phase solubility studies, drug content and in vitro dissolution studies. The best releasing dispersions were selected from release data, dissolution parameters and their release profiles. Solid state characterization techniques like Fourier transform infrared (FT-IR) spectroscopy, X-ray diffractometry, differential scanning calorimetry, near-infrared and Raman spectroscopy were used to characterize the drug in selected dispersions. The dispersions were also evaluated by wettability studies and permeation studies. The results of phase solubility studies... Tipo: Info:eu-repo/semantics/article Palavras-chave: Olanzapine; Mannitol; Solid dispersions. Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502012000200008 Comparative evaluation of pancreatic histopathology of rats treated with olanzapine, risperidone and streptozocin BJPS Shah,Rehmat; Subhan,Fazal; Sultan,Sayed Mohammad; Ali,Gowhar; Ullah,Ihsan; Ullah,Sami. Olanzapine and risperidone are widely prescribed atypical antipsychotics used in the treatment of schizophrenia and various other psychiatric disorders. Both of these drugs have been extensively reported to cause Type 2 diabetes mellitus and pancreatitis, however, the mechanism of olanzapine and risperidone-induced toxicity has not been so far unveiled. We, therefore, compared the streptozocin-induced pancreatic damage with that of pancreas isolated from olanzapine and risperidone treated rats. It was noticed that fibrotic growth, necrosis and derangement of the pancreatic islet cells caused by streptozocin were more pronounced than olanzapine and risperidone. Tipo: Info:eu-repo/semantics/article Palavras-chave: Histopathology/pancreas; Antipsychotic drugs/evaluation; Olanzapine; Risperidone. Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000300622 Registros recuperados: 4 Primeira ... 1 ... Última

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