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	Provedor de dados BJID (1) Autor Chuery,Ana Carolina Silva (1) Ribalta,Julisa Chamorro Lascasas (1) Silva,Ismael Dale Cotrim Guerreiro da (1) Speck,Neila Maria de Góis (1) Palavra-chave Arginine (1) Genetic polymorphisms (1) Human papillomavirus (1) Oncoproteins (1) P53 gene (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2017 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Association between the p53 arginine/arginine homozygous genotype at codon 72 and human papillomavirus E6/E7 mRNA expression BJID Chuery,Ana Carolina Silva; Silva,Ismael Dale Cotrim Guerreiro da; Ribalta,Julisa Chamorro Lascasas; Speck,Neila Maria de Góis. ABSTRACT Objective: To evaluate the association between p53 polymorphisms and human papillomavirus (HPV) E6/E7 mRNA expression. Methods: We analyzed 175 cervical samples from women aged 16-69 years old who were tested for HPV E6/E7 mRNA expression (NucliSENS® EasyQ® HPV). The samples were divided into three groups: positive (n = 75) those with positive HPV E6/E7 mRNA expression and positive high-risk HPV Hybrid Capture (HR-HC) test; negative (n = 52) those with negative HPV E6/E7 mRNA expression and positive HR-HC; and control (n = 48) those with negative HPV E6/E7 mRNA expression and negative HR-HC. The p53 polymorphisms at codons 11, 72, and 248 were evaluated through polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP).... Tipo: Info:eu-repo/semantics/article Palavras-chave: Human papillomavirus; Oncoproteins; Genetic polymorphisms; P53 gene; Arginine. Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702017000300248 Registros recuperados: 1 Primeira ... 1 ... Última

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