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	Provedor de dados Biol. Res. (2) BJMBR (1) Autor Al-Bari,Md. Abdul Alim (2) Hosen,Mohammad Jakir (2) Khatun,Amina (2) Mamun,Md. Abdullah Al (2) Alam,M. Masihul (1) Dai,Jinhua (1) Ge,Zhibin (1) Islam,Kamrul (1) Masihul Alam,M. (1) Zhang,Haijun (1) Zheng,Xingguo (1) Mais... Palavra-chave Osteoblast differentiation (3) Alkaline phosphatase (2) Bone formation (2) Bone fracture (1) MicroRNA-221 (1) Osteocalcin (1) Smad (1) Trabecular bone (1) Tridax procumbens flavonoids (1) Wnt/Notch (1) ZFPM2 (1) Mais... Tipo do documento Journal article (2) Info:eu-repo/semantics/article (1) Ano 2018 (1) 2017 (1) 2015 (1) País Chile (2) Brazil (1) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Tridax procumbens flavonoids: a prospective bioactive compound increased osteoblast differentiation and trabecular bone formation Biol. Res. Mamun,Md. Abdullah Al; Hosen,Mohammad Jakir; Khatun,Amina; Alam,M. Masihul; Al-Bari,Md. Abdul Alim. Abstract Background The Tridax procumbens extracts (TPE) are known for their ethno-medicinal properties to increase osteogenic functioning in mesenchymal stem cells. Recently, we found that the T. procumbens flavonoids (TPF) significantly suppressed the RANKL-induced osteoclasts differentiation and bone resorption. The TPF also promoted osteoblasts differentiation and bone formation demonstrated by increasing bone formation markers in cultured mouse primary osteoblasts. However, the effects of the TPF on in vivo bone formation remain unclear. In this study, we investigated the effects of the TPF on in vivo bone formation, injected the TPF (20 mg/kg) twice a day in the low calcium diet mice and killed them after 21 day. Radiographic and histomorphometric... Tipo: Journal article Palavras-chave: Alkaline phosphatase; Bone formation; Osteoblast differentiation; Tridax procumbens flavonoids; Trabecular bone. Ano: 2017 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602017000100221 Tridax procumbens flavonoids promote osteoblast differentiation and bone formation Biol. Res. Mamun,Md. Abdullah Al; Hosen,Mohammad Jakir; Islam,Kamrul; Khatun,Amina; Masihul Alam,M.; Al-Bari,Md. Abdul Alim. BACKGROUND: Tridaxprocumbens flavonoids (TPFs) are well known for their medicinal properties among local natives. Besides traditionally used for dropsy, anemia, arthritis, gout, asthma, ulcer, piles, and urinary problems, it is also used in treating gastric problems, body pain, and rheumatic pains of joints. TPFs have been reported to increase osteogenic functioning in mesenchymal stem cells. Our previous study showed that TPFs were significantly suppressed the RANKL-induced differentiation of osteoclasts and bone resorption. However, the effects of TPFs to promote osteoblasts differentiation and bone formation remain unclear. TPFs were isolated from Tridax procumbens and investigated for their effects on osteoblasts differentiation and bone formation by... Tipo: Journal article Palavras-chave: Alkaline phosphatase; Bone formation; Osteoblast differentiation; Osteocalcin. Ano: 2015 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602015000100065 MicroRNA-221 promotes cell proliferation, migration, and differentiation by regulation of ZFPM2 in osteoblasts BJMBR Zheng,Xingguo; Dai,Jinhua; Zhang,Haijun; Ge,Zhibin. Bone fracture is a common medical condition, which may occur due to traumatic injury or disease-related conditions. Evidence suggests that microRNAs (miRNAs) can regulate osteoblast differentiation and function. In this study, we explored the effects and mechanism of miR-221 on the growth and migration of osteoblasts using MC3T3-E1 cells. The expression levels of miR-221 in the different groups were measured by qRT-PCR. Then, miR-221 mimic and inhibitor were transfected into MC3T3-E1 cells, and cell viability and migration were measured using the CCK-8 assay and the Transwell migration assay. Additionally, the expression levels of differentiation-related factors (Runx2 and Ocn) and ZFPM2 were measured by qRT-PCR. Western blot was used to measure the... Tipo: Info:eu-repo/semantics/article Palavras-chave: MicroRNA-221; Bone fracture; Osteoblast differentiation; ZFPM2; Wnt/Notch; Smad. Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018001200602 Registros recuperados: 3 Primeira ... 1 ... Última

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