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Onabotulinumtoxin type A improves lower urinary tract symptoms and quality of life in patients with human T cell lymphotropic virus type 1 associated overactive bladder BJID
Carneiro Neto,Jose Abraão; Santos,Silvane Braga; Orge,Gloria Orge; Tanajura,Davi; Passos,Lucia; Oliveira,Cassius José; Andrade,Rosana; Melo,Cláudio Galeno de; Barroso Jr,Ubirajara; Carvalho,Edgar M..
ABSTRACT Aim: To evaluate the efficacy of the onabotulinum toxin type A in the treatment of HTLV-1 associated overactive bladder and its impact on quality of life (QoL). Methods: Case series with 10 patients with overactive bladder refractory to conservative treatment with anticholinergic or physical therapy. They received 200Ui of onabotulinumtoxin type A intravesically and were evaluated by overactive bladder symptoms score (OABSS) and King's Health Questionnaire. Results: The mean (SD) of the age was 52 + 14.5 years and 60% were female. All of them had confirmed detrusor overactivity on urodynamic study. Seven patients had HAM/TSP. The median and range of the OABSS was 13 (12–15) before therapy and decreased to 1.0 (0–12) on day 30 and to 03 (0–14)...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Overactive bladder; Onabotulinum toxin; HTLV-1.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000200079
Registros recuperados: 1
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