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The Investigation of the Relationship Between HSP-27 Release and Oxidative DNA Damage in Broiler Chickens with Tibial Dyschondroplasia by Using Histopathological and Immunohistochemical Methods Rev. Bras. Ciênc. Avic.
Kapakin,KAT; Kapakin,S; Imik,H; Gumus,R; Eser,G.
ABSTRACT Tibial dyschondroplasia (TD) is a skeletal disorder that occurs in the proximal metaphyses of tibiotarsus and sometimes tarsometatarsus, resulting in the development of avascularized and non-mineralized abnormal cartilage and causing significant economic loss. In this study, we aimed to show the histopathological changes and the relationship between the release of Heat-Shock Protein 27 (HSP-27) and oxidative DNA damage in broiler chickens with tibial dyschondroplasia, using histopathologic and immunohistochemical methods. Our study material consisted of totally 20 animals out of 42 days old 205 Ross 308 broiler chickens, 10 with TD lesions and 10 healthy control subjects. Tissue samples taken from animals performed necropsy was exposed to routine...
Tipo: Info:eu-repo/semantics/article Palavras-chave: HSP-27; Oxidative DNA damage; Tibial dyschondroplasia.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2019000300328
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