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First reported case of infective endocarditis caused by community-acquired methicillin-resistant Staphylococcus aureus not associated with healthcare contact in Brazil BJID
Fortes,Claudio Querido; Espanha,Claudia Adelino; Bustorff,Flavio Pedreira; Zappa,Bruno Cordeiro; Ferreira,Adriana Lucia Pires; Moreira,Regina Barbosa; Pereira,Nelson Gonçalves; Fowler Jr.,Vance G.; Deshmukh,Hitesh.
We report here the first case of endocarditis due to CA-MRSA not associated with healthcare contact in Brazil in Brazil. A previously healthy patient presented with history of endocarditis following a traumatic wound infection. Patient had multiple positive blood cultures within 72 h of admission and met modified Duke's criterion for infective endocarditis. The isolate was typed as Staphylococcal cassette chromosome (SCC) mec type IV and was positive for presence of Panton-Valentine leukocidin (PVL). Increased incidence of CA-MRSA endocarditis is a challenge for the internist to choose the best empirical therapy. Several authors have suggested an empirical therapy with both a beta-lactam and an anti-MRSA agent for serious S. aureus infections. Our patient...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Infective endocarditis; CA-MRSA; Brazil; PVL.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000600020
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The first report in Brazil of severe infection caused by community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) BJMBR
Rozenbaum,R.; Sampaio,M.G.; Batista,G.S.; Garibaldi,A.M.; Terra,G.M.F.; Souza,M.J.; Vieira,E.N.; Silva-Carvalho,M.C.; Teixeira,L.A.; Figueiredo,A.M.S..
Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) is an emergent pathogen in Brazil. However, there are no data on the prevalence of CA-MRSA. We report here the first well-characterized case of severe life-threatening CA-MRSA infection in a child living in Rio de Janeiro city. The patient had many complications including hematogenous osteomyelitis and involvement of multiple sites requiring drainage of soft-tissue abscess, and pleural and pericardial empyema. The MRSA isolates recovered were genotyped using PFGE, SCCmec typing and multilocus sequence typing. Disk diffusion tests were performed following Clinical and Laboratory Standards Institute recommendations. In addition, the presence of Panton-Valentine leukocidin (PVL) was...
Tipo: Info:eu-repo/semantics/other Palavras-chave: CA-MRSA; MRSA; PVL; S. aureus; Antimicrobial resistance.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000800011
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Hospital-associated methicillin-resistant Staphylococcus aureus carrying the PVL gene outbreak in a Public Hospital in Rio de Janeiro, Brazil BJM
Brust,Társis; Costa,Thaina Miranda da; Amorim,José Carlos; Asensi,Marise Dutra; Fernandes,Octavio; Aguiar-Alves,Fábio.
Hospital associated methicillin-resist Staphylococcus aureus has long been associated to outbreaks in the hospital environment. In this work, we investigated an outbreak of Hospital associated methicillin-resist Staphylococcus aureus carrying the Panton-Valentine leukocidin gene, which occurred in a large community hospital in Rio de Janeiro, Brazil.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Methicillin-resistant Staphylococcus aureus; Nasal colonization; Genotypes; PVL.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822013000300031
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