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| Shi,Lixin; Zhang,Lei; Wang,Chunyang; Sun,Shengkun; Cao,Xiyuan; Zhang,Xu. |
| Abstract Studies have demonstrated that miRNA-378 is expressed in various malignant tumors. In the present study, we aimed to explore the expression of serum miRNA-378 and its clinical significance in renal cell carcinoma (RCC) patients. A total of 75 RCC patients, 63 renal cysts (RC) patients and 75 healthy controls were selected. The miRNA-378 level in RCC and RC groups was significantly higher than in healthy control group, with RCC group having the highest level. The miRNA-378 levels were significantly decreased within the same group after surgery. When compared with healthy controls, RC group had higher levels but not significantly (p > 0.05) while levels in RCC group were significantly higher (p < 0.05). miRNA-378 expression was correlated with... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Renal cell carcinoma; MicroRNA 378; Diagnosis; Patients; AUC. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572017000300525 |
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| Costa,Luciano Bello; Ferraz,Maria Lucia Gomes; Perez,Renata M.; Ferreira,Adalgisa S.; Matos,Carla Adriana L.; Lanzoni,Valéria P.; Silva,Antônio Eduardo. |
| There is increasing interest in the identification of factors associated with liver disease progression in patients infected with hepatitis C virus (HCV). We assessed host-related factors associated with a histologically advanced stage of this disease and determined the rate of liver fibrosis progression in HCV-infected patients. We included patients submitted to liver biopsy, who were anti-HCV and HCV RNA positive, who showed a parenteral risk factor (blood transfusion or intravenous drug use), and who gave information about alcohol consumption.Patients were divided into two groups for analysis: group 1 - grades 0 to 2; group 2 - grades 3 to 4. The groups were compared in terms of sex, age at the time of infection, estimated duration of infection and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hepatitis C virus; Liver fibrosis; Patients. |
| Ano: 2002 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702002000500002 |
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