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	Provedor de dados BJMBR (2) Arq. Bras. Med. Vet. Zootec. (1) Autor Chiossi,M.P.V. (2) Roselino,A.M.F. (2) Aoki,V. (1) Costa,R.S. (1) Figueiredo,J.F.C. (1) Larsson Junior,C.E. (1) Larsson,C.E. (1) Mantovani,M.M. (1) Michalany,N.S. (1) Santana,A.E. (1) Severo,J.S. (1) Zeoti,D.M. (1) Mais... Palavra-chave Pemphigus foliaceus (3) Fogo selvagem (2) Anti-CD1a (1) Bullous dermatoses (1) Cytokines (1) DIF (1) Dendritic cells (1) IIF (1) Immunofluorescence (1) Langerhans cells (1) Pemphigus (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Info:eu-repo/semantics/other (1) Ano 2018 (1) 2004 (1) 2000 (1) País Brazil (3) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Comparative study of direct and indirect immunofluorescence for diagnosis of canine pemphigus foliaceus Arq. Bras. Med. Vet. Zootec. Severo,J.S.; Aoki,V.; Santana,A.E.; Mantovani,M.M.; Michalany,N.S.; Larsson Junior,C.E.; Larsson,C.E.. ABSTRACT Pemphigus foliaceus (PF) is the most common autoimmune skin disease in dogs. It is characterized by pustules, erosions, and crusts which occur due to the presence of autoantibodies that target intercellular adhesion. Histopathological examination is considered the gold standard pattern in the diagnosis, but may sometimes be inconclusive, especially when the characteristic findings are not identified. New diagnostic tests are continuously being developed and immunofluorescence assays, could be a valuable alternative diagnostic tool. This study aimed to evaluate the applicability of direct and indirect immunofluorescence (DIF and IIF) tests for the diagnosis of canine PF. Twenty eight dogs were divided into two groups: Group I with 14 dogs with PF... Tipo: Info:eu-repo/semantics/article Palavras-chave: Immunofluorescence; DIF; IIF; Pemphigus foliaceus. Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352018000300649 Dermal dendritic cell number correlates with serum autoantibody titers in Brazilian pemphigus foliaceus patients BJMBR Chiossi,M.P.V.; Costa,R.S.; Roselino,A.M.F.. Pemphigus foliaceus (PF) is an autoimmune bullous disease endemic in Brazil. Since serum IL-12 is increased in patients with PF and Langerhans cells (LC) produce IL-12, we titrated serum autoantibodies by indirect immunofluorescence, and quantified epidermal dendritic cells, known as LC, and dermal dendritic cells (DC). Biopsies of blistering lesions were obtained from 22 patients, 13 of whom were submitted to biopsy of both injured and of apparently healthy skin. The control groups consisted of skin from 8 cadavers and from 12 women submitted to breast plastic surgery. LC and DC were identified with anti-CD1a antibody and quantified by morphometric analysis. LC number in the lesion and in apparently healthy skin from PF patients was similar to that of... Tipo: Info:eu-repo/semantics/other Palavras-chave: Anti-CD1a; Dendritic cells; Fogo selvagem; Langerhans cells; Pemphigus foliaceus. Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000300008 Serum cytokines in patients with Brazilian pemphigus foliaceus (fogo selvagem) BJMBR Zeoti,D.M.; Figueiredo,J.F.C.; Chiossi,M.P.V.; Roselino,A.M.F.. Pemphigus foliaceus (PF) is characterized by acantholysis determined by IgG4 binding to desmoglein I, a 160-kDa desmosomal glycoprotein. To investigate the immunopathological aspects of Brazilian PF, we determined levels of serum cytokines in patients with PF. Twenty-five patients with PF and a control group consisting of 10 healthy individuals were studied. Serum IL-2, IL-4, IL-5, IL-10, IL-12 and IFN-gamma were measured in the two groups by ELISA. The median concentration of IL-2 was lower in PF patients compared to the control group (0.45 and 9.50 pg/ml, respectively), as also was the concentration of IL-4 (0.26 and 10.16 pg/ml, respectively). The same was observed for IL-5 (7.94 and 15.74 pg/ml, respectively) and for IFN-gamma (5.90 and 8.58 pg/ml,... Tipo: Info:eu-repo/semantics/article Palavras-chave: Cytokines; Pemphigus; Pemphigus foliaceus; Fogo selvagem; Bullous dermatoses. Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000900012 Registros recuperados: 3 Primeira ... 1 ... Última

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