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Production of 5-hydroxy-7-methoxy-4-methylphthalide in a culture of Penicillium crustosum Anais da ABC (AABC)
Valente,Angela M.M.P.; Ferreira,Antonio G.; Daolio,Cristina; Rodrigues Filho,Edson; Boffo,Elisangela F.; Souza,Antonia Q.L.; Sebastianes,Fernanda L.S.; Melo,Itamar S..
The chemical reactions carried out by microorganisms have been used as a tool in modern chemistry. This paper reports the production of mycophenolic acid and a new phthalide by the endophytic fungus Penicillium crustosum obtained from coffee seeds. The fungus was cultivated in a liquid medium for a period of seven days and after that the culture medium was divided into four treatments: A, B, C and D, to which different organic substances were added. Treatment A was maintained as the control to evaluate the occurrence of biotransformation. Organic acids were added to the culture media of treatments B (ferulic and quinic acids) and C [cinnamic and 3,4-(methylenedioxy) cinnamic acids], and caffeine was added in the treatment D. All these organic compounds...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Coffee; Endophytic fungus; Mycophenolic acid; Penicillium crustosum; 5-hydroxy-7-methoxy-4-methylphthalide.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652013000200487
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Microbial mediated preparation, characterization and optimization of gold nanoparticles BJM
Barabadi,Hamed; Honary,Soheila; Ebrahimi,Pouneh; Mohammadi,Milad Ali; Alizadeh,Ahad; Naghibi,Farzaneh.
The need for eco-friendly and cost effective methods for nanoparticles synthesis is developing interest in biological approaches which are free from the use of toxic chemicals as byproducts. This study aimed to biosynthesize and optimize the size of gold nanoparticles which produced by biotechnological method using Penicillium crustosum isolated from soil. Initially, Penicillium crustosum was grown in fluid czapek dox broth on shaker at 28 ºC and 200 rpm for ten days and then the supernatant was separated from the mycelia to convert AuCl4 solution into gold nanoparticles. The synthesized nanoparticles in the optimum conditions were formed with fairly well-defined dimensions and good monodispersity. The characterizations were done by using different methods...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Biosynthesis; Optimization; Gold nanoparticles; Box-behnken design; Penicillium crustosum.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000400046
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